The Autosomal Dominant Inheritance of Hereditary Gingival Fibromatosis: A Case Report.

The New York state dental journal Pub Date : 2016-11-01
B V Karthikeyan, Divya Khanna, M L V Prabhuji
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Abstract

Hereditary gingival fibromatosis (HGF) is a rare disorder characterized by progressive and varying degrees of gingival overgrowth. Oral manifestations vary from minimal to generalized enlargement, and HGF may occur as an isolated disorder or a feature of a syndrome. Unaesthetic appearance and functional impairment due to excessive gingival tissue dictate the need for surgical intervention. This article describes a family with three generations afflicted with a non-syndromic form of HGF with distinctive clinical, histological characteristics. Further, it highlights the need for genetic analysis and appropriate surgical technique to manage gingival enlargement and avoid recurrence.

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遗传性牙龈纤维瘤病常染色体显性遗传1例。
遗传性牙龈纤维瘤病(HGF)是一种罕见的疾病,其特征是进行性和不同程度的牙龈过度生长。口腔表现从轻微到全身性肿大不等,HGF可能作为一种孤立的疾病或综合征的特征发生。不美观的外观和功能损害,由于过多的牙龈组织决定了需要手术干预。这篇文章描述了一个家庭三代患有非综合征形式的HGF具有独特的临床,组织学特征。此外,它强调需要基因分析和适当的手术技术来管理牙龈扩大和避免复发。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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