Investigation of Antioxidant/Oxidant Status and Antimicrobial Activities of Lentinus tigrinus.

Q1 Pharmacology, Toxicology and Pharmaceutics Advances in Pharmacological Sciences Pub Date : 2018-11-01 eCollection Date: 2018-01-01 DOI:10.1155/2018/1718025

Mustafa Sevindik

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引用次数: 53

Abstract

In the present study, antioxidant and antimicrobial potential of the Lentinus tigrinus (Bull.) Fr. mushroom was determined. Total antioxidant status (TAS), total oxidant status (TOS), and oxidative stress index (OSI) of the mushroom were measured with Rel Assay kits. Antimicrobial activities were tested on 9 standard bacterial and fungal strains (Staphylococcus aureus, Staphylococcus aureus MRSA, Enterococcus faecalis, Escherichia coli, Pseudomonas aeruginosa, Acinetobacter baumannii, Candida albicans, Candida krusei, and Candida glabrata) with a modified agar dilution method. It was determined that the TAS value of L. tigrinus was 1.748 ± 0.071, TOS value was 19.294 ± 0.237, and OSI was 1.106 ± 0.031. It was also found that mushroom extracts generally exhibited higher activity on Candida albicans, C. krusei, and C. glabrata. In conclusion, it was suggested that L. tigrinus can be used as a natural source due to its antioxidant and antimicrobial activities.

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香菇抗氧化/氧化状态及抗菌活性的研究。

本文对香菇的抗氧化和抗菌活性进行了初步研究。测定了菌落。采用Rel Assay试剂盒测定蘑菇的总抗氧化状态(TAS)、总氧化状态(TOS)和氧化应激指数(OSI)。采用改良琼脂稀释法对金黄色葡萄球菌、金黄色葡萄球菌MRSA、粪肠球菌、大肠杆菌、铜绿假单胞菌、鲍曼不动杆菌、白色念珠菌、克鲁氏念珠菌、光秃念珠菌9株标准细菌和真菌进行抑菌活性测定。结果表明，虎耳鼠的TAS值为1.748±0.071,TOS值为19.294±0.237,OSI值为1.106±0.031。同时还发现，蘑菇提取物对白色念珠菌、克氏念珠菌和光秃念珠菌的活性普遍较高。综上所述，虎耳草具有抗氧化和抗菌活性，可作为天然来源加以利用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Advances in Pharmacological Sciences PHARMACOLOGY & PHARMACY-

CiteScore

6.40

自引率

0.00%

发文量

审稿时长

14 weeks

期刊介绍： Advances in Pharmacological and Pharmaceutical Sciences is a peer-reviewed, Open Access journal that publishes original research articles, review articles, and clinical studies in all areas of experimental and clinical pharmacology, pharmaceutics, medicinal chemistry and drug delivery. Topics covered by the journal include, but are not limited to: -Biochemical pharmacology, drug mechanism of action, pharmacodynamics, pharmacogenetics, pharmacokinetics, and toxicology. -The design and preparation of new drugs, and their safety and efficacy in humans, including descriptions of drug dosage forms. -All areas of medicinal chemistry, such as drug discovery, design and synthesis. -Basic biology of drug and gene delivery through to application and development of these principles, through therapeutic delivery and targeting. Areas covered include bioavailability, controlled release, microcapsules, novel drug delivery systems, personalized drug delivery, and techniques for passing biological barriers.