Mitral Valve Repair with a Semi-Rigid C-Band Annuloplasty Ring in Ischemic Mitral Regurgitation: Still a Viable Surgical Option?

Q3 Medicine Journal of Heart Valve Disease Pub Date : 2018-01-01
Guglielmo Saitto, Antonio Lio, Marco Russo, Francesca Nicolò, Carlo Bassano, Antonio Scafuri, Paolo Nardi, Giovanni Ruvolo
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引用次数: 0

Abstract

Background: Ischemic mitral valve regurgitation (IMR) develops in approximately 10% of patients after myocardial infarction. Surgical management of IMR is controversial, as many series have failed to demonstrate the superiority of mitral valve repair (MVRep) over mitral valve replacement (MVR) in IMR. Moreover, in the setting of MVRep, the choice of ring type is the subject of much debate. The study aim was to evaluate the results of MVRep in IMR with the use of a semi-rigid incomplete C-ring.

Methods: Between January 2006 and May 2014, a total of 105 patients (79 males, 26 females; mean age 69 ± 8 years) underwent surgical MVRep using a semi-rigid incomplete ring (median size 30 mm) during coronary artery bypass grafting (CABG) to treat IMR. The patients' mean logistic EuroSCORE was 14 ± 12, and the preoperative left ventricular ejection fraction was 43 ± 11%. The mean duration of follow up was 48 ± 31 months, and was 100% complete.

Results: In-hospital mortality was 6.6% (n = 7). The main predictor of in-hospital mortality was cardiopulmonary bypass time (p <0.05). Echocardiography performed at discharge showed moderate mitral regurgitation (MR) in only one patient, and significant reductions in left ventricular end-diastolic diameter (p <0.0001) and MR grade (p <0.0001). After seven years, freedom from all-cause death was 73 ± 9%, while freedoms from recurrence of MR grade ≥2 and NYHA class >II were 95 ± 3% and 89 ± 4%, respectively. Freedom from reintervention was 100%.

Conclusions: Despite the adverse prognosis of IMR, the present study demonstrated the effectiveness and durability of mitral valve repair with the use of a semi-rigid ring, as a concomitant procedure to CABG, showing good results in terms of recurrence of MR and event-free survival at mid-term follow up.

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半刚性c带环修复缺血性二尖瓣返流:仍是可行的手术选择?
背景:大约10%的心肌梗死患者发生缺血性二尖瓣返流(IMR)。IMR的手术治疗是有争议的,因为许多系列未能证明二尖瓣修复(MVRep)比二尖瓣置换术(MVR)在IMR中的优越性。此外,在MVRep的设置中,环类型的选择是许多争论的主题。本研究的目的是评价半刚性不完整c环在IMR中使用MVRep的结果。方法:2006年1月~ 2014年5月共收治105例患者,其中男79例,女26例;平均年龄69±8岁)在冠状动脉旁路移植术(CABG)中采用半刚性不完整环(中位直径30 mm)进行MVRep手术治疗IMR。患者的logistic EuroSCORE平均值为14±12,术前左室射血分数为43±11%。平均随访时间为48±31个月,100%完成。结果:院内死亡率为6.6% (n = 7),体外循环时间是院内死亡率的主要预测因子(p值分别为95±3%和89±4%)。再次干预的自由度为100%。结论:尽管IMR预后不良,但本研究表明,作为冠状动脉搭桥的伴随手术,使用半刚性环修复二尖瓣的有效性和持久性,在中期随访中,在MR复发和无事件生存方面显示出良好的效果。
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来源期刊
Journal of Heart Valve Disease
Journal of Heart Valve Disease 医学-心血管系统
CiteScore
1.00
自引率
0.00%
发文量
0
审稿时长
4-8 weeks
期刊介绍: The Journal of Heart Valve Disease (ISSN 0966-8519) is the official journal of The Society for Heart Valve Disease. It is indexed/abstracted by Index Medicus, Medline, Medlar, PubMed, Science Citation Index, Scisearch, Research Alert, Biomedical Products, Current Contents/Clinical Medicine. It is issued bi-monthly in one indexed volume by ICR Publishers Ltd., Crispin House, 12A South Approach, Moor Park, Northwood HA6 2ET, United Kingdom. This paper meets the requirements of ANSI standard Z39.48-1992 (Permanence of Paper).
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