HIV Care Continuum among Postpartum Women Living with HIV in Atlanta.

Q2 Medicine Infectious Diseases in Obstetrics and Gynecology Pub Date : 2019-02-14 eCollection Date: 2019-01-01 DOI:10.1155/2019/8161495
Christina M Meade, Martina Badell, Stephanie Hackett, C Christina Mehta, Lisa B Haddad, Andres Camacho-Gonzalez, Joy Ford, Marcia M Holstad, Wendy S Armstrong, Anandi N Sheth
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引用次数: 12

Abstract

Introduction: While increased healthcare engagement and antiretroviral therapy (ART) adherence occurs during pregnancy, women living with HIV (WLWH) are often lost to follow-up after delivery. We sought to evaluate postpartum retention in care and viral suppression and to identify associated factors among WLWH in a large public hospital in Atlanta, Georgia.

Methods: Data from the time of entry into prenatal care until 24 months postpartum were collected by chart review from WLWH who delivered with ≥20 weeks gestational age from 2011 to 2016. Primary outcomes were retention in HIV care (two HIV care visits or viral load measurements >90 days apart) and viral suppression (<200 copies/mL) at 12 and 24 months postpartum. Obstetric and contraception data were also collected.

Results: Among 207 women, 80% attended an HIV primary care visit in a mean 124 days after delivery. At 12 and 24 months, respectively, 47% and 34% of women were retained in care and 41% and 30% of women were virally suppressed. Attending an HIV care visit within 90 days postpartum was associated with retention in care at 12 months (aOR 3.66, 95%CI 1.72-7.77) and 24 months (aOR 4.71, 95%CI 2.00-11.10) postpartum. Receiving ART at pregnancy diagnosis (aOR 2.29, 95%CI 1.11-4.74), viral suppression at delivery (aOR 3.44, 95%CI 1.39-8.50), and attending an HIV care visit within 90 days postpartum (aOR 2.40, 95%CI 1.12-5.16) were associated with 12-month viral suppression, and older age (aOR 1.09, 95% CI 1.01-1.18) was associated with 24-month viral suppression.

Conclusions: Long-term retention in HIV care and viral suppression are low in this population of postpartum WLWH. Prompt transition to HIV care in the postpartum period was the strongest predictor of optimal HIV outcomes. Efforts supporting women during the postpartum transition from obstetric to HIV primary care may improve long-term HIV outcomes in women.

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亚特兰大产后感染艾滋病毒妇女的艾滋病毒护理连续性。
导语:虽然怀孕期间增加了医疗保健参与和抗逆转录病毒治疗(ART)的依从性,但感染艾滋病毒(WLWH)的妇女在分娩后往往得不到随访。我们试图评估在乔治亚州亚特兰大市的一家大型公立医院的产后留置护理和病毒抑制,并确定WLWH的相关因素。方法:采用图表复习法收集2011 ~ 2016年妊娠期≥20周分娩的产妇从产前护理开始至产后24个月的资料。主要结果是HIV护理的保留(两次HIV护理访问或病毒载量测量间隔>90天)和病毒抑制(结果:207名妇女中,80%在分娩后平均124天内参加了HIV初级保健访问。在12个月和24个月时,分别有47%和34%的妇女留在护理中,41%和30%的妇女病毒受到抑制。产后90天内参加HIV护理访问与产后12个月(aOR 3.66, 95%CI 1.72-7.77)和24个月(aOR 4.71, 95%CI 2.00-11.10)的护理保留相关。妊娠诊断时接受抗逆转录病毒治疗(aOR 2.29, 95%CI 1.11-4.74)、分娩时病毒抑制(aOR 3.44, 95%CI 1.39-8.50)以及产后90天内接受HIV护理访问(aOR 2.40, 95%CI 1.12-5.16)与12个月病毒抑制相关,年龄较大(aOR 1.09, 95%CI 1.01-1.18)与24个月病毒抑制相关。结论:在产后低死亡率人群中,HIV护理的长期保留率和病毒抑制率较低。产后及时过渡到艾滋病毒护理是最佳艾滋病毒结局的最强预测因子。在产后从产科过渡到艾滋病毒初级保健期间支持妇女的努力可能会改善妇女艾滋病毒的长期预后。
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来源期刊
Infectious Diseases in Obstetrics and Gynecology
Infectious Diseases in Obstetrics and Gynecology Medicine-Obstetrics and Gynecology
CiteScore
3.80
自引率
0.00%
发文量
17
审稿时长
12 weeks
期刊介绍: Infectious Diseases in Obstetrics and Gynecology aims to disseminate new and important information to clinicians and other health care providers, scientists, and researchers involved in the study or treatment of infectious diseases, especially those affecting the female patient. Its ultimate aim is to advance knowledge and encourage research, thereby improving the prevention or diagnosis and treatment of patients affected by such diseases.
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