All-Cause Mortality for Life Insurance Applicants with the Presence of Bundle Branch Block.

Q3 Medicine Journal of insurance medicine (New York, N.Y.) Pub Date : 2019-01-01 Epub Date: 2019-06-20 DOI:10.17849/insm-48-1-1-12.1
Stephen A Freitas, Ross MacKenzie, David N Wylde, Jason Von Bergen, J Carl Holowaty, Margaret Beckman, Steven J Rigatti, Daniel Zamarripa, Stacy Gill
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Abstract

Objective.-To determine the all-cause mortality of life insurance applicants who have a bundle branch block. Background.-Bundle branch block is an electrocardiographic pattern that has variable prognostic implications. Research studies have shown that both left and right bundle branch block are associated with increased mortality among cases that have heart disease. In the general population and life insurance applicant population, the prevalence of bundle branch block is relatively low, and its effects on long-term prognosis are not as well established. Methodology.-Life insurance applicants with reported bundle branch block were extracted from data covering United States residents between October 2009 and October 2016. Information about these applicants was matched to the Social Security Death Master (SSDMF) file for deaths occurring from 2009 to 2012 and to another commercially available death source file (Other Death Source, ODS) for deaths occurring from 2009 to 2016 to determine vital status. Actual to expected (A/E) mortality ratios were calculated using the Society of Actuaries 2015 Valuation Basic Table (2015VBT), select and ultimate table (age last birthday). All expected bases were not smoker distinct. Confidence bands around these mortality ratios were calculated. The variables of interest were applicant age, gender, location of the bundle branch block, and the presence of cardiac or cardiovascular conditions. Results.-There were 258,529.85 person-years exposure for applicants with bundle branch block. Of the applicants, 57.2% had right bundle branch block. Of person-years exposure, 11.5% had a cardiac condition along with the bundle branch block, and 4.4% had an underlying cardiovascular condition. Female mortality ratios were higher than those for males, but due to the low number of deaths, this difference was not significant. Left bundle branch block mortality ratios (1.01) were 1.4 times higher than those with right (0.74). Those applicants with a cardiac condition along with their bundle branch block had between 1.6 to 1.8 times the mortality ratio depending on the bundle branch block location, and those with a cardiovascular condition had between 1.5 to 1.7 times the mortality ratio over those applicants with just bundle branch block alone. Conclusion.-The presence of bundle branch block in an insurance applicant may be associated with increased all-cause mortality. In this study, life insurance applicants overall had a mortality slightly lower than the expected mortality based on the 2015 VBT. However, applicants with bundle branch block and a cardiac or cardiovascular comorbid condition had a significantly higher mortality ratio.

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存在束状分支块的人寿保险申请人的全因死亡率。
目标。-确定有束状分支阻滞的寿险投保人的全因死亡率。背景。束支传导阻滞是一种具有不同预后意义的心电图模式。研究表明,左束和右束分支阻滞与心脏病患者死亡率增加有关。在普通人群和寿险投保人群中,束支阻滞的患病率相对较低,其对长期预后的影响尚不清楚。方法。-从2009年10月至2016年10月期间美国居民的数据中提取报告捆绑分支块的人寿保险申请人。将这些申请人的信息与2009年至2012年死亡的社会保障死亡管理员(SSDMF)文件和2009年至2016年死亡的另一个商业死亡来源文件(其他死亡来源,ODS)进行匹配,以确定生命状态。实际与预期(A/E)死亡率的计算采用精算师协会2015年估值基本表(2015VBT)、选择表和最终表(年龄最后生日)。所有预期的碱基都不明显。计算了这些死亡率的置信区间。感兴趣的变量是申请人的年龄,性别,束支阻滞的位置,以及心脏或心血管疾病的存在。结果。-束状分支阻滞患者的暴露量为258,529.85人年。57.2%的申请人有右束分支阻滞。在人年暴露中,11.5%的人患有心脏疾病并伴有束支传导阻滞,4.4%的人患有潜在的心血管疾病。女性死亡率高于男性,但由于死亡人数较少,这种差异并不显著。左束支阻滞死亡率(1.01)是右束支阻滞死亡率(0.74)的1.4倍。根据束支阻滞的位置,患有心脏病并伴有束支阻滞的申请人的死亡率为1.6至1.8倍,患有心血管疾病的申请人的死亡率为仅束支阻滞的申请人的1.5至1.7倍。结论。投保人出现束支阻滞可能与全因死亡率增加有关。在本研究中,寿险申请人的总体死亡率略低于基于2015年VBT的预期死亡率。然而,束支阻滞和心脏或心血管合并症的患者死亡率明显更高。
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0.50
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6
期刊介绍: The Journal of Insurance Medicine is a peer reviewed scientific journal sponsored by the American Academy of Insurance Medicine, and is published quarterly. Subscriptions to the Journal of Insurance Medicine are included in your AAIM membership.
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