Clinical efficacy of a single injection of ceftiofur crystalline free acid sterile injectable suspension versus three daily injections of ceftiofur sodium sterile powder for the treatment of footrot in feedlot cattle.

Veterinary Therapeutics Pub Date : 2008-01-01
Joyce Van Donkersgoed, Marike Dussault, Pete Knight, Les Byers
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Abstract

A study was conducted in a feedlot in Alberta, Canada, to compare the clinical efficacy of a single injection of ceftiofur crystalline free acid sterile injectable suspension with three daily treatments of ceftiofur sodium sterile powder for the treatment of footrot. Use of a long-acting antimicrobial to treat footrot would reduce labor costs and hospital pen space requirements during high-risk periods. Four hundred cattle clinically diagnosed with footrot were systematically randomized to one of two treatment groups. The treatment success rate at 14 days after treatment (99.5% for ceftiofur crystalline free acid sterile injectable suspension and 99.0% for ceftiofur sodium sterile powder for injection) was not statistically different (P>.05) between the two drugs.

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单次注射头孢替弗结晶游离酸无菌注射混悬液与每日三次注射头孢替弗钠无菌粉剂治疗饲养场牛足疾的临床疗效。
在加拿大阿尔伯塔省的一个饲养场进行了一项研究,比较了单次注射头孢替呋结晶无酸无菌注射混悬液与每日三次注射头孢替呋钠无菌粉剂治疗足癣的临床疗效。在高风险时期,使用长效抗菌药物治疗足癣可以降低劳动力成本和医院围栏空间需求。400头临床诊断为足疾的牛被系统地随机分为两个治疗组。治疗后第14天,两种药物的治疗成功率(头孢替弗无结晶酸性注射用无菌混悬液为99.5%,注射用头孢替弗钠无菌粉剂为99.0%)差异无统计学意义(P> 0.05)。
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