Peripheral Neuropathic Pain and Pain Related to Complex Regional Pain Syndrome with and without Fixed Dystonia - Efficient Therapeutic Approach with Local Anesthetics.

IF 1.5 Q3 ANESTHESIOLOGY Local and Regional Anesthesia Pub Date : 2020-01-31 eCollection Date: 2020-01-01 DOI:10.2147/LRA.S229315
Thomas Michels
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引用次数: 1

Abstract

Peripheral Neuropathic Pain (PNP) as well as the Complex Regional Pain Syndrome (CRPS), also known as "Reflex Sympathetic Dystrophy", or "Sudeck Dystrophy", all of them have a poor prognosis. The numerous therapeutic offers are rarely accompanied by convincing success over a long duration of time. Even worse is the prognosis of a fixed dystonia which may develop in the extremities of PNP or CRPS patients. In literature a few cases are reported in which the often unbearable pain of those patients with or without a disabling dystonia disappeared immediately after the injection of local anesthetics (LAs) into the scars of a preceding trauma. This review evaluates publications concerning the neuropathological characteristics of fixed dystonia in PNP/CRPS patients and the electrophysiological processes of scar neuromas. The results of these evaluations support the understanding of the therapeutic successes and their immediate results reported above by the injection of LAs into triggering scars. Therapeutic options are discussed.

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伴有或不伴有固定肌张力障碍的周围神经性疼痛和与复杂区域疼痛综合征相关的疼痛——局部麻醉药的有效治疗方法。
外周神经性疼痛(PNP)以及复杂区域疼痛综合征(CRPS),又称“反射性交感神经营养不良”或“Sudeck营养不良”,均预后较差。大量的治疗方案很少伴随着长期的令人信服的成功。更糟糕的是,固定肌张力障碍的预后可能发生在PNP或CRPS患者的四肢。在文献中报道了一些病例,这些患者有或没有致残性肌张力障碍,通常难以忍受的疼痛在向先前创伤的疤痕注射局麻药(LAs)后立即消失。本文综述了有关PNP/CRPS患者的固定肌张力障碍的神经病理特征和疤痕性神经瘤的电生理过程的出版物。这些评估的结果支持了上述通过将LAs注射到触发疤痕的治疗成功及其直接结果的理解。讨论了治疗方案。
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来源期刊
CiteScore
6.30
自引率
0.00%
发文量
12
审稿时长
16 weeks
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