The biology and t heories of aging.

IF 1.5 4区 生物学 Q4 Agricultural and Biological Sciences Theoretical Biology Forum Pub Date : 2019-01-01 DOI:10.19272/201911402006
Snežana M Stanić, Sanja Lj Matić
{"title":"The biology and t heories of aging.","authors":"Snežana M Stanić,&nbsp;Sanja Lj Matić","doi":"10.19272/201911402006","DOIUrl":null,"url":null,"abstract":"<p><p>Aging is a natural, time-dependent process characterized by irreversible changes in the molecules, cells, tissues, and organs. It occurs as a result of cumulative damage at different levels of the organization, in particular by damaging proteins and DNA. There is no single definition, nor a unique attitude about when and how age arises and what are its causes. The process is extremely complex and most likely a consequence of the effects of different mechanisms (not only genetic but also acquired) that lead to disrupt homeostasis, reduce stress resistance and the more frequent occurrence of the disease. There are many classifications of theories about aging and they often contradict one another. No one theory is sufficiently able to explain the process of aging. The aim of this work is to analyze the different aspects, main characteristics of the aging, individual differences in the speed of this process and theories about the mechanisms of aging.</p>","PeriodicalId":54453,"journal":{"name":"Theoretical Biology Forum","volume":null,"pages":null},"PeriodicalIF":1.5000,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Theoretical Biology Forum","FirstCategoryId":"99","ListUrlMain":"https://doi.org/10.19272/201911402006","RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Agricultural and Biological Sciences","Score":null,"Total":0}
引用次数: 1

Abstract

Aging is a natural, time-dependent process characterized by irreversible changes in the molecules, cells, tissues, and organs. It occurs as a result of cumulative damage at different levels of the organization, in particular by damaging proteins and DNA. There is no single definition, nor a unique attitude about when and how age arises and what are its causes. The process is extremely complex and most likely a consequence of the effects of different mechanisms (not only genetic but also acquired) that lead to disrupt homeostasis, reduce stress resistance and the more frequent occurrence of the disease. There are many classifications of theories about aging and they often contradict one another. No one theory is sufficiently able to explain the process of aging. The aim of this work is to analyze the different aspects, main characteristics of the aging, individual differences in the speed of this process and theories about the mechanisms of aging.

查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
衰老的生物学和理论。
衰老是一种自然的、依赖时间的过程,其特征是分子、细胞、组织和器官发生了不可逆转的变化。它的发生是由于组织的不同层次累积损伤的结果,特别是通过破坏蛋白质和DNA。对于年龄何时、如何产生以及产生的原因,没有单一的定义,也没有唯一的态度。这一过程极其复杂,很可能是不同机制(不仅是遗传的,而且是后天的)影响的结果,这些机制导致体内平衡被破坏,抗逆性降低,疾病发生的频率更高。关于衰老的理论有很多分类,它们经常相互矛盾。没有任何一种理论能够充分解释衰老的过程。本研究的目的是分析衰老的不同方面、主要特征、衰老速度的个体差异以及衰老机制的理论。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 去求助
来源期刊
Theoretical Biology Forum
Theoretical Biology Forum 生物-生物学
CiteScore
0.70
自引率
0.00%
发文量
0
审稿时长
>12 weeks
期刊最新文献
Editorial. The third-way third wave and the enduring appeal of bioexceptionalism. Origins and demise of selfish gene theory. Biological relativity revisited: the pre-eminent role of values. Evolution in two parts: as seen in a new fram ework for biology.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1