A Cold Atmospheric Pressure Plasma Discharge Device Exerts Antimicrobial Effects.

Kenneth A Cornell, Kate Benfield, Tiffany Berntsen, Jenna Clingerman, Adam Croteau, Spencer Goering, Daniel Moyer, Mariah Provost, Amanda White, Don Plumlee, Julia T Oxford, Jim Browning
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Abstract

A cold atmospheric pressure plasma device was developed using two parallel plates of Low Temperature Co-fired Ceramic with embedded electrodes. The 2.4 cm wide by 1 mm deep plasma discharge operates at 20 kHz with a 2-5 kV AC drive signal across a 0.25 mm gap. Mixed Argon/oxygen plasmas were directed between the plates to flow toward a bacterial biofilm sample for treatment. Results showed that at 4-5 kV the plasma etched away a bacterial biofilm on glass in 10 minutes. In addition, we showed that short plasma treatments rapidly killed biofilm resident bacteria with ED90 values of <15 s.

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低温常压等离子体放电装置的抗菌作用。
研制了一种低温常压等离子体装置。2.4厘米宽,1毫米深的等离子放电工作在20千赫,2-5千伏的交流驱动信号跨越0.25毫米的间隙。混合氩/氧等离子体被引导到板之间,流向细菌生物膜样品进行处理。结果表明,在4-5千伏电压下,等离子体在10分钟内腐蚀掉玻璃上的细菌生物膜。此外,我们发现短时间等离子体处理能快速杀死ED90值为的生物膜驻留细菌
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