Predictive value of perfusion index for mortality in mechanically ventilated patients.

IF 2.7 4区 医学 Q3 ENDOCRINOLOGY & METABOLISM Aging Male Pub Date : 2020-12-01 Epub Date: 2020-05-06 DOI:10.1080/13685538.2020.1760816
Mehmet Can Er, Cengiz Kaya, Yasemin Burcu Ustun, Ali Haydar Sahinoglu
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引用次数: 3

Abstract

Aim: This study aimed to examine the prognostic significance of the perfusion index (PI) in mechanically ventilated patients.

Methods: Study included sixty patients who had the risk factors for the development of acute respiratory distress syndrome and received mechanical ventilator (MV) support in intensive care unit (ICU) unit between January 2017/January 2018. The demographic characteristics, vital signs, blood gas parameters, lactate levels, prognostic scores, and use of inotropic drugs were recorded. Arterial blood gas and PI measurements at the frontal region were performed at the time of and 12th and 24th hours of admission to the ICU. The patients were followed up for 60 days, and the outcome was recorded.

Results: Twelve patients (20%) died during the first 7 days, and 27 patients (45%) died within 60 days of the admission. Multivariate analyses to determine potential predictors of 7 and 30-day mortality showed that only 24th-hour lactate level was independent predictor of 60-day mortality, and the PI at 24th was the sole independent predictor of 7-day mortality.

Conclusion: The PI did not predict 60-day mortality in MV patients who had risk factors for the development of Acute Respiratory Distress Syndrome (ARDS). However, the PI at 24th may be a significant predictor of 7-day mortality.

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灌注指数对机械通气患者死亡率的预测价值。
目的:探讨灌注指数(PI)对机械通气患者预后的影响。方法:选取2017年1月至2018年1月间在重症监护病房(ICU)接受机械呼吸机(MV)支持的60例急性呼吸窘迫综合征危险因素患者作为研究对象。记录患者的人口学特征、生命体征、血气参数、乳酸水平、预后评分和肌力药物使用情况。分别于入院第12、24小时进行额区动脉血气和PI测量。随访60 d,记录结果。结果:12例患者(20%)在入院前7天死亡,27例患者(45%)在入院后60天内死亡。确定7天和30天死亡率潜在预测因子的多变量分析显示,只有24小时乳酸水平是60天死亡率的独立预测因子,24小时PI是7天死亡率的唯一独立预测因子。结论:PI不能预测具有急性呼吸窘迫综合征(ARDS)危险因素的MV患者60天死亡率。然而,24日的PI可能是7天死亡率的重要预测因子。
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来源期刊
Aging Male
Aging Male 医学-泌尿学与肾脏学
CiteScore
6.40
自引率
3.80%
发文量
33
审稿时长
>12 weeks
期刊介绍: The Aging Male , the official journal of the International Society for the Study of the Aging Male, is a multidisciplinary publication covering all aspects of male health throughout the aging process. The Journal is a well-recognized and respected resource for anyone interested in keeping up to date with developments in this field. It is published quarterly in one volume per year. The Journal publishes original peer-reviewed research papers as well as review papers and other appropriate educational material that provide researchers with an integrated perspective on this new, emerging specialty. Areas of interest include, but are not limited to: Diagnosis and treatment of late-onset hypogonadism Metabolic syndrome and related conditions Treatment of erectile dysfunction and related disorders Prostate cancer and benign prostate hyperplasia.
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