Bile duct injury outcomes following cholecystectomy: a cross sectional study.

IF 1.4 Q4 IMMUNOLOGY American journal of clinical and experimental immunology Pub Date : 2020-06-15 eCollection Date: 2020-01-01
Sepehr Eslami, Lotfallah Abedini, Nazanin Vahedi Nouri, Mehdi Rabiee, Milad Kabiri Samani
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Abstract

Background: Considering the importance of the repairing time in patients with biliary duct injury, the aim of this study was to evaluate the outcomes of patents with bile duct injury following cholecystectomy.

Methods: In this cross sectional study that was conducted on 64 patients with bile duct injury following cholecystectomy was referred to Shafa hospital in Tehran-Iran during 2010-2019 due to repair of biliary duct. Then patients were divided into two groups based on early and late referring time after bile duct injury, the postoperative outcomes were evaluated in two groups.

Results: The alanine transaminase (ALT) and the aspartate aminotransferase (AST) in the late group were significantly higher than the early group. There were significant differences between the two groups based on the results of endoscopic retrograde cholangiopancreatography (ERCP) and magnetic resonance cholangiopancreatography (MRCP) (P < 0.05). The frequency of bile duct dilatation, cholangitis and itching in late group were significantly higher than early group, also the frequency of uncomplicated outcome in the early group were significantly more than late group (P < 0.05).

Conclusion: The postoperative complication of biliary duct injury reduced, if patients diagnosed and referred at the same early stages (early referral).

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胆囊切除术后胆管损伤的结果:一项横断面研究。
背景:考虑到胆管损伤患者修复时间的重要性,本研究的目的是评估胆囊切除术后胆管损伤患者的预后。方法:对2010-2019年期间因胆管修复而转诊至伊朗德黑兰沙法医院的64例胆囊切除术后胆管损伤患者进行横断面研究。然后根据胆管损伤后的早期和晚期转诊时间将患者分为两组,评估两组患者的术后预后。结果:晚期组丙氨酸转氨酶(ALT)、天冬氨酸转氨酶(AST)显著高于早期组。内镜逆行胰胆管造影(ERCP)与磁共振胰胆管造影(MRCP)结果比较,两组差异有统计学意义(P < 0.05)。晚期组胆管扩张、胆管炎、瘙痒发生率显著高于早期组,无并发症发生率显著高于晚期组(P < 0.05)。结论:胆管损伤患者早期确诊和早期转诊可减少术后并发症。
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