Definitive Treatment Of Primary Spontaneous Pneumothorax A 10 Year Experience.

Eva Brysch, João Gonçalves, Ricardo Ferreira, André Sena, Francisco Freitas, Paula Monteiro, Ângelo Nobre, Cristina Bárbara
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Abstract

Objectives: Primary spontaneous pneumothorax (PSP) is defined as a pneumothorax without obvious underlying lung disease. Definitive treatment should be offered to patients with recurrent or persistent PSP. The aim of this study was to compare the effectiveness of medical pleurodesis (MP) with video assisted thoracic surgery (VATS) on definitive treatment of PSP.

Methods: 10 years' retrospective study of PSP patients that underwent VATS or MP. Baseline characteristics, perioperative and follow-up data were compared.

Results: A total of 133 patients were included (MP=54; VATS=79). Baseline characteristics were similar between groups, with a male predominance (MP 83.6 vs VATS 85.5%) with a mean age of 24.78 and 25.81 years old, respectively. Post interventional length of hospital stay was similar (MP 4.94 vs VATS 4.47 days, p=0.20), but chest tube duration was longer in the VATS group (MP 2.94 vs VATS 3.56 days, p=0.03). The overall complications rate was low with no statistically significant difference between groups (MP 5/54 vs VATS 7/79, p=1.00). Regarding the follow-up, MP had a significant higher PSP recurrence rate (MP 11.1% vs VATS 1.3%, p=0.042), most occurring over the first two years.

Conclusion: Despite both MP and VATS are safe methods with short hospital stay and few complications associated, the results of this study show that VATS had a significantly lower rate of recurrences. Overall, VATS should be offered as the first line treatment to patients with PSP.

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原发性自发性气胸的明确治疗:10年经验。
目的:原发性自发性气胸(PSP)是指无明显肺部基础疾病的气胸。对于复发性或持续性PSP患者应给予明确的治疗。本研究的目的是比较内科胸膜融合术(MP)与视频辅助胸外科手术(VATS)对PSP最终治疗的有效性。方法:对接受VATS或MP治疗的PSP患者进行10年回顾性研究。比较两组患者的基线特征、围手术期及随访资料。结果:共纳入133例患者(MP=54;大桶= 79)。组间基线特征相似,男性为主(MP 83.6 vs VATS 85.5%),平均年龄分别为24.78岁和25.81岁。介入后住院时间相似(MP 4.94 vs VATS 4.47天,p=0.20),但VATS组胸管持续时间更长(MP 2.94 vs VATS 3.56天,p=0.03)。总并发症发生率较低,组间差异无统计学意义(MP 5/54 vs VATS 7/79, p=1.00)。在随访中,MP的PSP复发率明显更高(MP 11.1% vs VATS 1.3%, p=0.042),大多数发生在前两年。结论:尽管MP和VATS都是安全的方法,住院时间短,并发症少,但本研究结果显示VATS的复发率明显较低。总之,VATS应作为PSP患者的一线治疗。
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