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Revista portuguesa de cirurgia cardio-toracica e vascular : orgao oficial da Sociedade Portuguesa de Cirurgia Cardio-Toracica e Vascular最新文献

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The Meeting 会议
Alix Ohlin
Hilbert University — There are two major theories of probability, one due to von Mises and the other due to Kolmogorov. The first requires the existence of a collective before probabilities can be defined. Its motivation is physical. The second postulates a probability space which is purely mathematical. It makes probability a branch of mathematics. We show that von Mises’ theory is more appropriate to application in quantum theory. Kolomogorov’s theory can lead to paradoxical results.
RICHTER, SULLIVAN,国家大气研究中心—在位于海气界面上方的大气表层,大风可以将大量的海沫喷射到上方的湍流中。紊流表层的这种分散相是否能改变从空气到海洋表面的动量转移,这个问题仍然没有解决。因此,这项研究的目的是确定和解释在紊流、粒子流中壁法向动量传递的变化。这是通过使用离散相的拉格朗日点粒子表示的直接数值模拟(DNS)完成的。选择湍流库埃特流,是因为它表现出与大气表层相似的某些特征,研究了不同浓度和大小的球形非相互作用颗粒。一般来说,分散相的加入破坏了导致湍流、载流子相动量转移的运动,同时通过额外的分散相应力补偿了这种动量转移的损失。本文将介绍紊流壁-法向动量输运中这些变化的机理和解释。
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引用次数: 0
Abstracts of the SPCCTV 4D Visions 20, 28-29 November 2020, Figueira da Foz, Portugal. 2020 年 11 月 28-29 日葡萄牙 Figueira da Foz 举行的 SPCCTV 4D Visions 20 会议摘要。

Oral communications about Cardiac Surgery, Thoracic Surgery and Vascular Surgery presented at the SPCCTV 4D Visions 20, 28-29 November 2020, Figueira da Foz, Portugal.

在 2020 年 11 月 28-29 日于葡萄牙 Figueira da Foz 举行的 SPCCTV 4D Visions 20 上就心脏外科、胸外科和血管外科进行口头交流。
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引用次数: 0
Multiple Vs Single Arterial Grafting In Coronary Surgery Among Diabetic Patients: A Meta-Analysis. 糖尿病患者冠状动脉手术中多动脉与单动脉移植的Meta分析。
F. Saraiva, Joao Leite-Moreira, António S. Barros, A. Leite-Moreira, A. Lourenço
Introduction The use of more than one arterial conduit in coronary surgery has been widely associated with better long-term results. Objectives We sought to investigate the benefits of Multiple Arterial Grafts (MAG) over Single Arterial Grafts (SAG), among diabetic patients, in short and long-term results throughout a meta-analysis of propensity score matching (PSM) studies. Materials and Methods MEDLINE and ISI Web of Science were used to find relevant literature (1960-2018). We included cohort studies with at least 200 patients and that reported one of these outcomes: long-term survival, early mortality or sternal wound infection (SWI). Survival was collected through hazard ratio (HR) along with their variance and the other endpoints using frequencies or odds ratio (OR) from the matched sample. Fixed effect models were used to compute statistical combined measures and 95% confidence intervals (CI). Results Eleven studies were included performing a total of 9670 diabetic patients: 4833 MAG and 4837 SAG (1:1 PSM in all studies). MAG group consisted in bilateral internal mammary artery (BIMA) in 8 studies; single IMA (SIMA)+radial artery (RA) in 5 studies; and one study reported several MAG approaches: BIMA+RA+Gastroepiploic artery (GEA), SIMA+RA+GEA, SIMA+GEA or BIMA+GEA. SAG group consisted in SIMA with or without saphenous vein graft in all studies, except for one that included also patients with GEA instead of SIMA. Ten studies reported long-term survival and mean follow-up time ranged from 5 to 12 years (max. follow-up 30y). Overall, MAG had significantly improved long-term survival compared with SAG (pooled HR=0.79, CI95%: 0.74-0.85,p<0.01). In-hospital mortality was reported by 6 studies (4202 patients: 2099 MAG and 2103 SAG) and occurred in 3.0% vs. 3.3% in MAG vs. SAG patients, respectively (pooled OR: 0.91, CI95%: 0.65-1.29,p=0.60). SWI was reported by 6 studies (4432 patients: 2216 MAG and 2216 SAG) and occurred in 2.8% vs. 2.2% in MAG vs. SAG patients, respectively (pooled OR: 1.31, CI95%: 0.90- 1.92,p=0.15). Excluding one article in which MAG group consisted in IMA+RA, the remaining 5 BIMA vs. SIMA studies reported an higher risk of SWI in MAG group (pooled OR: 1.63, CI95%: 1.07-2.49,p=0.02) Conclusions Considering PSM studies, MAG provides superior long-term survival compared to SAG in diabetic patients. This surgical technique does not implement additional risk regarding in- -hospital mortality, but MAG with BIMA was associated with a higher risk of SWI in this specific subgroup of patients.
引言在冠状动脉外科手术中使用多个动脉导管可以获得更好的长期效果。目的通过对倾向评分匹配(PSM)研究的荟萃分析,我们试图在短期和长期结果中调查糖尿病患者中多动脉移植物(MAG)优于单动脉移植物的益处。材料与方法利用MEDLINE和ISI科学网检索相关文献(1960-2018)。我们纳入了至少200名患者的队列研究,这些研究报告了其中一个结果:长期生存率、早期死亡率或胸骨伤口感染(SWI)。通过风险比(HR)及其方差和其他终点,使用匹配样本的频率或比值比(or)收集生存率。固定效应模型用于计算统计组合测量和95%置信区间(CI)。结果共有11项研究对9670名糖尿病患者进行了研究:4833例MAG和4837例SAG(所有研究均为1:1 PSM)。MAG组包括8项研究中的双侧乳内动脉(BIMA);单IMA(SIMA)+桡动脉(RA)5项研究;一项研究报道了几种MAG方法:BIMA+RA+胃网膜动脉(GEA)、SIMA+RA+GEA、SIMA+GEA或BIMA+GEA。在所有研究中,SAG组均包括有或无隐静脉移植物的SIMA,除了一项也包括GEA而非SIMA患者。10项研究报告了长期生存率,平均随访时间为5-12年(最长随访30年)。总体而言,与SAG相比,MAG显著提高了长期生存率(合并HR=0.79,CI95%:0.74-0.85,p<0.01)。6项研究报告了住院死亡率(4202名患者:2099名MAG和2103名SAG),MAG与SAG患者的住院死亡率分别为3.0%和3.3%,6项研究报告了SWI(4432名患者:2216名MAG和2216名SAG),MAG和SAG患者的SWI发生率分别为2.8%和2.2%(合并OR:1.31,CI95%:0.90-1.92,p=0.15)。不包括一篇MAG组为IMA+RA的文章,其余5篇BIMA和。SIMA研究报告称,MAG组发生SWI的风险更高(合并OR:1.63,CI95%:1.07-2.49,p=0.02)。结论考虑到PSM研究,与糖尿病患者的SAG相比,MAG提供了更高的长期生存率。这种手术技术并没有增加住院死亡率的风险,但MAG和BIMA在这一特定亚组患者中与更高的SWI风险相关。
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引用次数: 0
Safety And Risk Factors For The Morbidity And Mortality Of Pneumonectomy: A Retrospective 10- Year Study In A Single Institution. 全肺切除术发病率和死亡率的安全性和危险因素:一项单一机构的10年回顾性研究。
Joana Rei, Susana Lareiro, Pedro Fernandes, Patrícia Castro, Sara S Costa, José Miranda, Luís Vouga, Miguel Guerra

Objectives: Pneumonectomy is a procedure with high post-operative morbidity and mortality. This study aims to assess and identify possible risk factors that can affect post-operative outcome, therefore determining the safety of pneumonectomy in specific groups.

Methods: A total of 63 patients submitted to pneumonectomy at our centre, from February 2008 to February 2018, were included in our retrospective study. Age, gender, side of intervention, diagnosis, pre-operative symptoms, substance abuse and comorbidities were assessed. Early and late post-operative complications, as well as death were our major outcomes. We analysed the impact of preoperative variables on major outcomes using SPSS statistics.

Results: We found a 9,8% surgery-related mortality and 1-year survival rate of 76,2%. The incidence of early complications in our population was of 35% while eleven patients (17,4%) developed late post-operative complications. No statistical difference was found when comparing survival time between genders or age groups. Right sided pneumonectomies seem to be associated with an higher mortality risk. No other association between risk factors and outcomes reached statistical significance in both univariate and multivariate analysis.

Conclusions: Pneumonectomy is a viable option regardless of age whenever the patient has a good functional and cardiopulmonary status. Gender and diagnostic group do not seem to influence adverse event risk, although right-sided pneumonectomies show an increased risk for post-operative death. Care should be taken with patients submitted to neoadjuvant therapy. All patients should be encouraged to cease smoking as early as possible before surgery, given the increased risks for post-operative complications.

目的:全肺切除术是一种术后发病率和死亡率高的手术。本研究旨在评估和识别可能影响术后预后的危险因素,从而确定特定人群全肺切除术的安全性。方法:2008年2月至2018年2月,我们的回顾性研究纳入了63例在我们中心接受全肺切除术的患者。评估年龄、性别、干预方式、诊断、术前症状、药物滥用和合并症。术后早期和晚期并发症以及死亡是我们的主要结果。我们使用SPSS统计分析术前变量对主要结局的影响。结果:手术相关死亡率为9.8%,1年生存率为76.2%。本组患者早期并发症发生率为35%,其中11例(17.4%)出现术后晚期并发症。在比较不同性别和年龄组的生存时间时,没有发现统计学差异。右侧肺切除术似乎与较高的死亡风险相关。在单因素和多因素分析中,危险因素和结果之间没有其他关联达到统计学意义。结论:肺切除术是一个可行的选择,无论年龄,只要病人有良好的功能和心肺状态。性别和诊断组似乎不影响不良事件风险,尽管右侧肺切除术显示术后死亡风险增加。患者接受新辅助治疗时应注意。考虑到术后并发症的风险增加,应鼓励所有患者在手术前尽早戒烟。
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引用次数: 0
Complex Mediastinal Tumour In Pregnancy: Case Report. 妊娠期复杂纵隔肿瘤1例。
Cristina Rodrigues, Daniel Cabral, Isabel Correia, Luísa Pinto, Mónica Centeno, Francisco Félix

A 19 years-old woman, on her 17th week of pregnancy presented to the emergency department with thoracic pain and vomiting. An empyema was diagnosed and she was transferred to a tertiary hospital for treatment. After drainage of the empyema a mediastinal mass was detected and a thoracic MRI revealed a multicystic lesion of the anterior mediastinum, causing cardiac and left lung compression, suggestive of a complicated teratoma. After a multidisciplinary discussion involving pulmonology, radiology, obstetrics and thoracic surgery, she was operated successfully by clamshell incision. A mature complicated teratoma was resected and a left pleurectomy/decortication performed. She was discharged on day 17 with no obstetrical or respiratory symptoms..

一名19岁女性,怀孕17周时因胸痛和呕吐就诊于急诊科。经诊断为脓胸,她被转到三级医院治疗。肺气肿引流后,发现纵隔肿块,胸部MRI显示前纵隔多囊病变,引起心脏和左肺压迫,提示合并畸胎瘤。经肺科、放射科、产科、胸外科等多学科联合讨论,采用翻盖式切口手术成功。我们切除了一个成熟的复杂畸胎瘤,并进行了左胸膜切除术/去皮术。她于第17天出院,无产科或呼吸道症状。
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引用次数: 0
Complex Aortoiliac Pelvic And Visceral Revascularization. 复杂主动脉、髂、盆腔和内脏血管重建术。
António Pereira-Neves, João Rocha-Neves, Luís Duarte-Gamas, Alfredo Cerqueira, Ricardo Gouveia

Aortoiliac occlusive disease (AIOD) remains an area of debate concerning open and endovascular treatment options. A case of a 63-year old female is reported, with previous known vascular intermittent claudication, that presented in the emergency room with acute ischemia of the right lower limb with 24-hours of evolution. The computer tomographic angiography unveiled occlusion of the superior mesenteric artery, occlusion of left common iliac artery (CIA), subocclusive stenosis of right CIA, occlusion of distal runoffs vessels in the right lower limb and diffuse aorto-iliac disease. The first approach was to place the patient under catheter directed thrombolysis (48h) which led to right pedal pulse recovery but the occlusion of left CIA remained. The patient was then electively submitted to Covered Endovascular Repair of Aortic Bifurcation (CERAB) with chimney to inferior mesenteric artery and with an additional bailout left iliac sandwich due to dissection. Distal pulses are still present after 18 months of follow-up. Endovascular techniques provide a low morbimortality option with similar symptomatic improvement, challenging open surgery as the standard of care even in complex AIOD.

主动脉髂闭塞性疾病(AIOD)仍然是一个关于开放和血管内治疗选择的争论领域。报告一例63岁女性,既往已知血管性间歇性跛行,在急诊室表现为右下肢急性缺血24小时演变。计算机断层血管造影显示肠系膜上动脉闭塞、左髂总动脉闭塞、右髂总动脉闭下狭窄、右下肢远端径流血管闭塞及弥漫性主动脉-髂病变。第一种方法是将患者置于导管引导下溶栓(48小时),导致右侧踏板脉搏恢复,但左侧中央动脉闭塞仍然存在。随后,患者选择性地接受了导管至肠系膜下动脉的主动脉分叉覆盖血管内修复术(CERAB),以及因夹层导致的左髂夹层额外救助术。随访18个月后远端脉搏仍然存在。血管内技术提供了一种低死亡率的选择,具有类似的症状改善,即使在复杂的AIOD中,开放手术作为标准治疗也面临挑战。
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引用次数: 0
Endometriosis Unusual Aetiology Of Inguinal Swelling. 子宫内膜异位症腹股沟肿胀的不寻常病因。
Catarina Longras, Sandrina Figueiredo Braga, Celso Carrilho, Amílcar Mesquita

A 42 years-old female presented with right inguinal swelling with one year of evolution. Magnetic resonance imaging was suggestive of inguinal endometriosis adherent to femoral vessels. Due to the rarity of this pathology (prevalence 0.3-0.6%), clinical suspicion is essential. Surgical excision is the treatment of choice.

一个42岁的女性表现为右腹股沟肿胀与一年的发展。磁共振成像提示腹股沟子宫内膜异位症附着股血管。由于罕见的病理(患病率0.3-0.6%),临床怀疑是必要的。手术切除是治疗的首选。
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引用次数: 0
Endovascular Treatment Of A Symptomatic Thoracic Aorta Thrombi. 症状性胸主动脉血栓的血管内治疗。
Pedro Pinto Sousa, Pedro Sá Pinto

Aortic mural thrombus is a rare condition with 0.45% incidence in the general population, being the thoracic aorta the most affected portion. In the absence of an atherosclerotic wall lesion, other specific conditions should be studied and excluded. The authors describe two clinical cases of a 64 years old male and a 48 years old female that despite a non- -atherosclerotic diseased aorta, had a thoracic mural thrombus which presented clinically with mesenteric and lower limb microembolization, respectively. Once presented with peripheral embolization, the aim should be to exclude the embolic source and prevent end organ malfunction. TEVAR has been developed as a therapeutic solution to exclude the embolic source, with a high rate of technical success and few comorbidities associated. Long term anti-coagulation is debatable but may prevent further embolization events.

主动脉壁血栓是一种罕见的疾病,在普通人群中发病率为0.45%,是胸主动脉最受影响的部分。在没有动脉粥样硬化壁病变的情况下,应研究并排除其他特殊情况。作者描述了两例临床病例,一名64岁的男性和一名48岁的女性,尽管有非动脉粥样硬化性病变主动脉,但有胸壁血栓,临床分别表现为肠系膜和下肢微栓塞。一旦提出外周栓塞,目的应是排除栓塞源和防止终末器官功能障碍。TEVAR已经发展成为一种排除栓塞源的治疗方案,技术成功率高,相关合并症少。长期抗凝是有争议的,但可以防止进一步的栓塞事件。
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引用次数: 0
Fibromuscular Dysplasia Of The Renal Arteries. 肾动脉纤维肌肉发育不良。
Luísa Amado Costa, Eduardo Rosa, João Leitão, Luís Vítor

A 48 year-old female patient presented with arterial hypertension. Computed tomography angiography revealed small stenoses alternating with areas of dilatation (due to small fusiform aneurysms) in the middle to distal portions of the main renal arteries, creating a "string of beads" appearance, findings in keeping with fibromuscular dysplasia.

一位48岁的女性患者以动脉高血压为主诉。计算机断层血管造影显示肾主动脉中远端小狭窄与扩张区交替(由于小梭状动脉瘤),形成“串珠状”外观,与纤维肌肉发育不良相一致。
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引用次数: 0
Early And Midterm Outcomes Following Aortic Valve Replacement With Mechanical Versus Bioprosthetic Valves In Patients Aged 50 To 70 Years. 50 - 70岁患者机械主动脉瓣置换术与生物瓣膜置换术的早期和中期结果
Rafael Rocha, Rui Cerqueira, Francisca A Saraiva, Soraia Moreira, António S Barros, Jorge Almeida, Mário J Amorim, André P Lourenço, Paulo Pinho, Adelino Leite-Moreira

Objectives: To compare 7-year survival and freedom from reoperation, as well as early clinical and hemodynamic outcomes, after surgical aortic valve replacement (SAVR) with mechanical or bioprosthetic valves in patients aged 50-70 years.

Methods: single-center retrospective cohort study including adults aged 50-70 years who underwent SAVR in 2012 with a mechanical or bioprosthetic valve. Median follow-up was 7 years. Univariable analyses were performed using Kaplan-Meier curves and Log-Rank tests for survival and freedom from reoperation analyses. Multivariable time-to-event analyses were conducted using Cox Regression.

Results: Of a total of 193 patients, 76 (39.4%) received mechanical valves and 117 (60.6%) received bioprosthetic valves. A trend for better survival was found for mechanical prostheses when adjusting for EuroSCORE II (HR: 0.35; 95%CI: 0.12-1.02, p=0.054), but using a backward stepwise Cox regression prosthesis type was not retained by the model as an independent predictor of survival. Moreover, mechanical prostheses showed trends for higher freedom from reoperation (100% vs. 95.5%, Log-Rank, p=0.076), higher median EuroSCORE II (2.52% vs. 1.95%, p=0.06) and early mortality (7.9% vs. 2.6%, p=0.086). However, after adjusting for EuroSCORE II, there was no significant difference in early mortality (OR: 2.3, 95%CI: 0.5-10.5, p=0.272). Regarding hemodynamic performance at follow-up echocardiogram, there were no differences other than left ventricular mass regression, which was not as pronounced in the mechanical group (-12% vs. -21%, p=0.002).

Conclusion: Mechanical and bioprosthetic aortic valves prostheses showed similar mid-term survival in the 50-70 age group. Further prospective and larger studies are needed to provide evidence-based recommendations on this topic.

目的:比较50-70岁患者主动脉瓣置换术(SAVR)与机械或生物瓣膜置换术后的7年生存率和免再手术,以及早期临床和血流动力学结果。方法:采用单中心回顾性队列研究,纳入2012年接受机械或生物人工瓣膜置换术的50-70岁成人。中位随访时间为7年。单变量分析采用Kaplan-Meier曲线和Log-Rank检验进行生存和免于再手术分析。采用Cox回归进行多变量时间-事件分析。结果:193例患者中,机械瓣膜76例(39.4%),生物瓣膜117例(60.6%)。当调整EuroSCORE II时,发现机械假体有更好的生存趋势(HR: 0.35;95%CI: 0.12-1.02, p=0.054),但采用后向逐步Cox回归,模型不保留假体类型作为生存的独立预测因子。此外,机械假体具有更高的再手术自由度(100%比95.5%,Log-Rank, p=0.076)、更高的EuroSCORE II中位数(2.52%比1.95%,p=0.06)和早期死亡率(7.9%比2.6%,p=0.086)。然而,在调整EuroSCORE II后,早期死亡率无显著差异(OR: 2.3, 95%CI: 0.5-10.5, p=0.272)。关于随访超声心动图的血流动力学表现,除了左心室质量下降外,没有其他差异,机械组的差异不明显(-12% vs -21%, p=0.002)。结论:在50 ~ 70岁年龄组,机械主动脉瓣修复术与生物主动脉瓣修复术中期生存率相近。需要进一步的前瞻性和更大规模的研究来提供关于这一主题的循证建议。
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引用次数: 0
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Revista portuguesa de cirurgia cardio-toracica e vascular : orgao oficial da Sociedade Portuguesa de Cirurgia Cardio-Toracica e Vascular
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