Pharmacological considerations of antibiotic failures in bovine respiratory disease cases.

IF 4.3 2区 农林科学 Q1 VETERINARY SCIENCES Animal Health Research Reviews Pub Date : 2020-12-01 Epub Date: 2020-12-02 DOI:10.1017/S1466252320000122
Brian V Lubbers
{"title":"Pharmacological considerations of antibiotic failures in bovine respiratory disease cases.","authors":"Brian V Lubbers","doi":"10.1017/S1466252320000122","DOIUrl":null,"url":null,"abstract":"<p><p>Bovine respiratory disease (BRD) is one of the most common indications for antimicrobial therapy in beef cattle production and research trials demonstrate that antibiotic therapy greatly improves clinical outcome for BRD. These trials also show that BRD treatment success rates are less than 100% and that there are opportunities to optimize antimicrobial prescribing and improve clinical outcomes if the underlying cause(s) of BRD treatment failures can be identified and addressed. As the etiology of BRD in an individual animal is frequently multi-factorial in nature; it is likely that BRD treatment failures also result from complex interactions between the drug, drug administrator, animal host, pathogens, and the environment. This review will focus specifically on the pharmacological aspects, specifically the interactions between the host and the drug and the drug and the drug administrator, of BRD treatment failures and the actions that veterinary practitioners can take to investigate and mitigate therapeutic failures in future cases.</p>","PeriodicalId":51313,"journal":{"name":"Animal Health Research Reviews","volume":"21 2","pages":"177-178"},"PeriodicalIF":4.3000,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1017/S1466252320000122","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Animal Health Research Reviews","FirstCategoryId":"97","ListUrlMain":"https://doi.org/10.1017/S1466252320000122","RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2020/12/2 0:00:00","PubModel":"Epub","JCR":"Q1","JCRName":"VETERINARY SCIENCES","Score":null,"Total":0}
引用次数: 0

Abstract

Bovine respiratory disease (BRD) is one of the most common indications for antimicrobial therapy in beef cattle production and research trials demonstrate that antibiotic therapy greatly improves clinical outcome for BRD. These trials also show that BRD treatment success rates are less than 100% and that there are opportunities to optimize antimicrobial prescribing and improve clinical outcomes if the underlying cause(s) of BRD treatment failures can be identified and addressed. As the etiology of BRD in an individual animal is frequently multi-factorial in nature; it is likely that BRD treatment failures also result from complex interactions between the drug, drug administrator, animal host, pathogens, and the environment. This review will focus specifically on the pharmacological aspects, specifically the interactions between the host and the drug and the drug and the drug administrator, of BRD treatment failures and the actions that veterinary practitioners can take to investigate and mitigate therapeutic failures in future cases.

查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
牛呼吸道疾病病例中抗生素失效的药理学考虑。
牛呼吸道疾病(BRD)是肉牛生产中最常见的抗微生物治疗适应症之一,研究试验表明,抗生素治疗可大大改善BRD的临床结果。这些试验还表明,BRD治疗成功率低于100%,如果能够确定和解决BRD治疗失败的根本原因,就有机会优化抗菌药物处方并改善临床结果。由于动物个体BRD的病因通常是多因素的;BRD治疗失败也可能是药物、药物管理者、动物宿主、病原体和环境之间复杂的相互作用造成的。这篇综述将特别关注BRD治疗失败的药理学方面,特别是宿主与药物、药物与药物管理者之间的相互作用,以及兽医从业者在未来病例中可以采取的调查和减轻治疗失败的行动。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 去求助
来源期刊
Animal Health Research Reviews
Animal Health Research Reviews VETERINARY SCIENCES-
CiteScore
6.70
自引率
0.00%
发文量
8
期刊介绍: Animal Health Research Reviews provides an international forum for the publication of reviews and commentaries on all aspects of animal health. Papers include in-depth analyses and broader overviews of all facets of health and science in both domestic and wild animals. Major subject areas include physiology and pharmacology, parasitology, bacteriology, food and environmental safety, epidemiology and virology. The journal is of interest to researchers involved in animal health, parasitologists, food safety experts and academics interested in all aspects of animal production and welfare.
期刊最新文献
Recent advances in the use of bacterial probiotics in animal production Alternatives to antibiotics in veterinary medicine: considerations for the management of Johne's disease. Essential oils and essential oil compounds in animal production as antimicrobials and anthelmintics: an updated review. Evidence that ectoparasites influence the hematological parameters of the host: a systematic review. Applications of butyric acid in poultry production: the dynamics of gut health, performance, nutrient utilization, egg quality, and osteoporosis - CORRIGENDUM.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1