Quality of Life in Elders with Suspected Alzheimer Disease: An Urban Health Centers-Based Study from Iran.

IF 1.4 Q4 CLINICAL NEUROLOGY Dementia and Geriatric Cognitive Disorders Extra Pub Date : 2020-11-16 eCollection Date: 2020-09-01 DOI:10.1159/000511397

Behnam Honarvar, Elahe Khaksar, Fatemeh Jafari, Mohammad Hassan Zahedroozegar, Sanaz Amiri

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引用次数: 3

Abstract

Background/aims: Quality of life (QOL) and Alzheimer disease (AD) among older people have been recognized as public health challenges. Here, we investigated the association between QOL and AD in the elders.

Methods: In this cross-sectional study, elderly people were selected from urban health centers (Shiraz, Iran) by multistage cluster random sampling and were interviewed using LEIPAD (for QOL) and Montreal Cognitive Assessment (for AD) questionnaires. The data was analyzed using Mplus (version 6.12) and IBM SPSS (version 25) software.

Results: The participants consisted of 182 elderly with a mean age of 67 ± 5.05 years, and 95 (52.2%) of them were females. There were 161 (88.5%) and 130 (71.4%) cases educated up to 12 years and married, respectively. Furthermore, 46 (25.3%) had low-to-moderate QOL, and 132 (72.5%) were suspected to have AD. QOL was inversely associated with AD, and men (β = -0.310) were more affected than women (β = -0.290). AD (β = -0.298), age (β = -0.288), hypertension (β = -0.267), education (β = 0.260), and body mass index (β = -0.198) were determinants of QOL. Also, physical activity was indirectly associated with QOL (β = 0.076). AD was correlated with the cognitive functioning component of QOL (r = -0.72).

Conclusion: One elder out of 4, did not have desirable QOL and 3 elders out of 4 were suspected to have AD. AD can decrease QOL among the older people. Screening of the elders for AD is recommended to improve their QOL by health centers.

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怀疑患有阿尔茨海默病的老年人的生活质量:一项来自伊朗城市卫生中心的研究

背景/目的:老年人的生活质量(QOL)和阿尔茨海默病(AD)已被认为是公共卫生挑战。在这里，我们研究了老年人生活质量与AD之间的关系。方法:采用多阶段整群随机抽样的方法，在伊朗设拉子(Shiraz)的城市卫生中心抽取老年人，采用LEIPAD (QOL)和Montreal Cognitive Assessment (AD)问卷进行访谈。采用Mplus (version 6.12)软件和IBM SPSS (version 25)软件对数据进行分析。结果:老年人182人，平均年龄67±5.05岁，其中女性95人(52.2%)。受教育程度在12岁以下的有161例(88.5%)，已婚的有130例(71.4%)。此外，46例(25.3%)生活质量中低，132例(72.5%)怀疑患有AD。生活质量与AD呈负相关，男性(β = -0.310)比女性(β = -0.290)受影响更大。AD (β = -0.298)、年龄(β = -0.288)、高血压(β = -0.267)、受教育程度(β = 0.260)和体重指数(β = -0.198)是影响生活质量的因素。体力活动与生活质量间接相关(β = 0.076)。AD与生活质量的认知功能成分相关(r = -0.72)。结论:1 / 4的老年人生活质量不理想，3 / 4的老年人怀疑患有AD。老年痴呆症会降低老年人的生活质量。健康中心建议对老年人进行阿尔茨海默病筛查以改善他们的生活质量。

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来源期刊

Dementia and Geriatric Cognitive Disorders Extra Medicine-Psychiatry and Mental Health

CiteScore

4.30

自引率

0.00%

发文量

审稿时长

9 weeks

期刊介绍： This open access and online-only journal publishes original articles covering the entire spectrum of cognitive dysfunction such as Alzheimer’s and Parkinson’s disease, Huntington’s chorea and other neurodegenerative diseases. The journal draws from diverse related research disciplines such as psychogeriatrics, neuropsychology, clinical neurology, morphology, physiology, genetic molecular biology, pathology, biochemistry, immunology, pharmacology and pharmaceutics. Strong emphasis is placed on the publication of research findings from animal studies which are complemented by clinical and therapeutic experience to give an overall appreciation of the field. Dementia and Geriatric Cognitive Disorders Extra provides additional contents based on reviewed and accepted submissions to the main journal Dementia and Geriatric Cognitive Disorders Extra .