Christina N M Ryan, Meletios N Doulgkeroglou, Dimitrios I Zeugolis
{"title":"Electric field stimulation for tissue engineering applications.","authors":"Christina N M Ryan, Meletios N Doulgkeroglou, Dimitrios I Zeugolis","doi":"10.1186/s42490-020-00046-0","DOIUrl":null,"url":null,"abstract":"<p><p>Electric fields are involved in numerous physiological processes, including directional embryonic development and wound healing following injury. To study these processes in vitro and/or to harness electric field stimulation as a biophysical environmental cue for organised tissue engineering strategies various electric field stimulation systems have been developed. These systems are overall similar in design and have been shown to influence morphology, orientation, migration and phenotype of several different cell types. This review discusses different electric field stimulation setups and their effect on cell response.</p>","PeriodicalId":72425,"journal":{"name":"BMC biomedical engineering","volume":"3 1","pages":"1"},"PeriodicalIF":0.0000,"publicationDate":"2021-01-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1186/s42490-020-00046-0","citationCount":"41","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"BMC biomedical engineering","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1186/s42490-020-00046-0","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 41
Abstract
Electric fields are involved in numerous physiological processes, including directional embryonic development and wound healing following injury. To study these processes in vitro and/or to harness electric field stimulation as a biophysical environmental cue for organised tissue engineering strategies various electric field stimulation systems have been developed. These systems are overall similar in design and have been shown to influence morphology, orientation, migration and phenotype of several different cell types. This review discusses different electric field stimulation setups and their effect on cell response.
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