Efficacy of Rituharitaki (seasonal adjuvant of Haritaki) on disorders of Varsha Ritu (monsoon) w.s.r. to quality of life: An open labelled randomized controlled clinical trial.

Ayu Pub Date : 2019-10-01 Epub Date: 2021-01-14 DOI:10.4103/ayu.AYU_243_18
A V Smitha, K V Dilipkumar
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Abstract

Background: Monsoon epidemics are always a serious concern in the public health sector. Administration of Haritaki with suitable vehicle as per season (Rituharitaki) is a simple, cost-effective preventive measure which can be used for such conditions.

Aims and objectives: Study objectives were to assess the effect of Rituharitaki in preventing the diseases in Varsha Ritu (monsoon) and its effect on the WHO quality of life BREF (QOL BREF), total leukocyte count (TLC), differential count (DC) and erythrocyte sedimentation rate (ESR) in healthy volunteers.

Materials and methods: From 82 participants, based on inclusion criteria, 60 participants were selected and randomly allocated into trial and control group of 30 each using a computer generated random number table. Intervention given was Rituharitaki (Terminalia chebula Retz) in tablet form-3 tablets of 1g each and Saindhava (rock salt) 1g with lukewarm water at 6.30 am on empty stomach to the participants of trial group for 60 days in Varsha Ritu in Kerala and were observed during this period.

Results: The results were analyzed using Chi-square test and paired t-test. Significant results were obtained in the trial group in reducing the severity and frequency of common cold (p < 0.001), cough (p < 0.05), and fever (p < 0.001). In the WHO QOL BREF domain 1 & 4 showed significant result in the trial group (p < 0.05). Among the haematological parameters - total leukocyte count (TLC), eosinophil count and erythrocyte sedimentation rate (ESR) were statistically significant reduced (p < 0.05) in the trial group.

Conclusion: Rituharitaki is found to be effective in reducing severity and frequency of diseases in Varsha Ritu and had effect on quality of life of patients.

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Rituharitaki (Haritaki季节性佐剂)治疗季风性疾病对生活质量的影响:一项开放标签随机对照临床试验。
背景:季风流行病一直是公共卫生部门严重关切的问题。根据季节使用合适的车辆管理哈里塔基(Rituharitaki)是一种简单,具有成本效益的预防措施,可用于这种情况。目的和目的:研究目的是评估Rituharitaki在预防Varsha Ritu (monsoon)疾病中的作用及其对健康志愿者WHO生活质量BREF (QOL BREF)、总白细胞计数(TLC)、差异计数(DC)和红细胞沉降率(ESR)的影响。材料与方法:根据纳入标准,从82名受试者中选择60名,采用计算机生成的随机数字表随机分为试验组和对照组各30名。在喀拉拉邦的瓦尔沙里图,试验组的参与者在早上6点30分空腹给予Rituharitaki (Terminalia chebula Retz)片剂形式-3片1g, Saindhava(岩盐)1g,为期60天,并在此期间进行观察。结果:结果采用卡方检验和配对t检验进行分析。试验组在降低普通感冒的严重程度和频率(p < 0.001)、咳嗽(p < 0.05)和发烧(p < 0.001)方面取得了显著的结果。在WHO QOL中,实验组BREF域1和4有显著差异(p < 0.05)。在血液学指标中,试验组总白细胞计数(TLC)、嗜酸性粒细胞计数(eosinophill)、红细胞沉降率(ESR)均显著降低(p < 0.05)。结论:Rituharitaki能有效降低Varsha Ritu患者疾病的严重程度和频率,并对患者的生活质量有影响。
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