A case report of allergic bronchopulmonary mycosis caused by Alternaria alternata in colonization of Aspergillus.

IF 4.6 Q2 MATERIALS SCIENCE, BIOMATERIALS ACS Applied Bio Materials Pub Date : 2024-09-01 DOI:10.12932/AP-101020-0981

Min Ju Jo, Yoomi Yeo, Kyueng-Whan Min, Sung Jun Chung, Tai Sun Park, Hyun Lee, Dong Won Park, Ji-Yong Moon, Jang Won Sohn, Sang-Heon Kim, Ho Joo Yoon, Tae-Hyung Kim

{"title":"A case report of allergic bronchopulmonary mycosis caused by Alternaria alternata in colonization of Aspergillus.","authors":"Min Ju Jo, Yoomi Yeo, Kyueng-Whan Min, Sung Jun Chung, Tai Sun Park, Hyun Lee, Dong Won Park, Ji-Yong Moon, Jang Won Sohn, Sang-Heon Kim, Ho Joo Yoon, Tae-Hyung Kim","doi":"10.12932/AP-101020-0981","DOIUrl":null,"url":null,"abstract":"Background: Allergic bronchopulmonary aspergillosis (ABPA) is a pulmonary disease caused by a complex hypersensitivity reaction to colonization of the airways with various fungi. ABPA caused by Alternaria alternata, other than Aspergillus spp., is named Allergic bronchopulmonary mycosis (ABPM).Objective: To describe the first case of ABPM caused by Alternaria alternata in East Asia.Methods: Case report.Results: A 58-year-old female visited our hospital due to an abnormal chest x-ray, following chest computed tomography (CT) revealed consolidation in the left lower lobe. On laboratory finding, eosinophil count and total IgE level were high. The skin prick test and specific IgE for Alternaria alternata were positive. After diagnosis of ABPM, the patient was treated with prednisolone without antifungal agents, and her chest image was much improved.Conclusions: Aspergillus is most common etiology of allergic pulmonary disease, however, Alternaria should be considered even though positive culture of Aspergillus spp.","PeriodicalId":2,"journal":{"name":"ACS Applied Bio Materials","volume":null,"pages":null},"PeriodicalIF":4.6000,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"ACS Applied Bio Materials","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.12932/AP-101020-0981","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"MATERIALS SCIENCE, BIOMATERIALS","Score":null,"Total":0}

引用次数: 0

Abstract

Background: Allergic bronchopulmonary aspergillosis (ABPA) is a pulmonary disease caused by a complex hypersensitivity reaction to colonization of the airways with various fungi. ABPA caused by Alternaria alternata, other than Aspergillus spp., is named Allergic bronchopulmonary mycosis (ABPM).

Objective: To describe the first case of ABPM caused by Alternaria alternata in East Asia.

Methods: Case report.

Results: A 58-year-old female visited our hospital due to an abnormal chest x-ray, following chest computed tomography (CT) revealed consolidation in the left lower lobe. On laboratory finding, eosinophil count and total IgE level were high. The skin prick test and specific IgE for Alternaria alternata were positive. After diagnosis of ABPM, the patient was treated with prednisolone without antifungal agents, and her chest image was much improved.

Conclusions: Aspergillus is most common etiology of allergic pulmonary disease, however, Alternaria should be considered even though positive culture of Aspergillus spp.

查看原文

微信好友朋友圈 QQ好友复制链接

本刊更多论文

一例由交替交替孢霉和曲霉定植引起的过敏性支气管肺霉菌病病例报告。

背景：过敏性支气管肺曲霉菌病（ABPA）是一种由各种真菌在气道中定植引起的复杂超敏反应导致的肺部疾病。由除曲霉菌属以外的交替交替孢霉引起的过敏性支气管肺曲霉病（ABPA）被命名为过敏性支气管肺曲霉病（ABPM）：描述东亚首例由交替交替孢霉引起的过敏性支气管肺霉菌病：方法：病例报告：一名 58 岁女性因胸部 X 光片异常来我院就诊，胸部计算机断层扫描（CT）显示其左下叶有合并症。化验结果显示，嗜酸性粒细胞计数和总 IgE 水平较高。皮肤点刺试验和交替孢霉的特异性 IgE 呈阳性。确诊为 ABPM 后，患者接受了泼尼松龙治疗，但未使用抗真菌药物，胸部影像也大为改善：结论：曲霉菌是过敏性肺部疾病最常见的病原体，但即使曲霉菌属培养阳性，也应考虑到交替孢霉属。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文去求助

来源期刊