Small Dysplastic Oral Leucoplakia in a Smoking Woman: a Case Report.

IF 1 Q3 DENTISTRY, ORAL SURGERY & MEDICINE eJournal of Oral Maxillofacial Research Pub Date : 2021-03-31 eCollection Date: 2021-01-01 DOI:10.5037/jomr.2021.12105
Caique Mariano Pedroso, Gustavo Keller Schemberger, João Lucas Dziadzio, Letícia Caroline Condolo, Priscila de Camargo Smolarek
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Abstract

Background: Oral leucoplakia is clinical term used to describe white plaques, and that is part of the group of oral potentially malignant disorders. Leucoplakia may show epithelial dysplasia, mainly in harder smoking patient. This case report discusses a small leucoplakia with dysplasia on the tongue's lateral border in a woman, diagnosed early after a routine clinical consultation.

Methods: A 57-year-old female patient consulted to the Oral Diagnosis and Surgery Service of the State University of Ponta Grossa, Brazil. First, the patient was referred for the extraction of her lower incisors due to periodontal disease. During clinical examination, was identified a sessile white plaque, of small size, and located on the tongue's left lateral border. Thus, the lesion's diagnostic hypothesis was oral leucoplakia due to patient be chronic smoker for 40 years. The incisional biopsy was performed, with the epithelial tissue and part of the connective tissue removed.

Results: The histopathological examination revealed a stratified and keratinized pavement epithelium, with cellular atypia, and presence of hyperchromatism and nuclear pleomorphism. However, the alterations were restricted to the epithelium's basal, characterizing a mild dysplasia. The proposed treatment was surgical removal of the lesion, and the patient was also instructed to quit smoking, as well as she continues to follow-up.

Conclusions: The presented case emphasizes the importance of early diagnosis and the orientation of risk factors to smoking patients, even in small lesions that can clinically appear harmless.

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吸烟女性口腔小的发育不良白斑1例报告。
背景:口腔白斑是用于描述白色斑块的临床术语,是口腔潜在恶性疾病的一部分。白斑可表现为上皮发育不良,主要见于重度吸烟患者。这个病例报告讨论了一个小的白斑与发育不良的舌侧边界的妇女,诊断早期后,常规的临床咨询。方法:一名57岁女性患者就诊于巴西蓬塔格罗萨州立大学口腔诊断与外科服务部。首先,病人因牙周病被转介去拔下门牙。在临床检查中,发现了一个无梗的白色斑块,小尺寸,位于舌的左侧外侧边界。因此,该病变的诊断假设是由于患者长期吸烟40年导致的口腔白斑。行切口活检,切除上皮组织和部分结缔组织。结果:组织病理学检查显示层状和角化路面上皮,细胞异型性,存在深染和核多形性。然而,这些改变仅限于上皮的基底,表现为轻度发育不良。建议的治疗方法是手术切除病变,并指示患者戒烟,并继续随访。结论:本病例强调了吸烟患者早期诊断和危险因素定位的重要性,即使是临床上看似无害的小病变。
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审稿时长
12 weeks
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