Serological study of celiac disease in children with dental caries.

Q3 Medicine Human Antibodies Pub Date : 2021-01-01 DOI:10.3233/HAB-210445

Gholamreza Kalvandi, Iraj Shahramian, Abbas Farmany, Shirin Yadegari, Fateme Parooie

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引用次数: 2

Abstract

Background: Celiac disease is a common gastrointestinal autoimmune disorder. Studies have shown that the prevalence of tooth decay is high in patients with celiac disease. This study was performed to evaluate the serology of celiac disease in children with dental caries.

Methods: Children aged 3 to 12 years who referred to the dental clinic with enamel caries were included in the study. Celiac disease was assessed by measuring serum IgA levels and anti-TTG (Anti TTG (IgA)) antibodies. Then, by analyzing the collected data, the prevalence of celiac disease in children with dental caries and its relationship with various variables were investigated.

Results: 120 children, 56 girls (46.7%) and 64 boys (53.3%) with dental caries were involved in this study. The positive celiac serology rate of studied population was 14 (11.6%). Based on the results of this study, a significant relationship was obtained between maternal education, sex and place of residence and celiac disease (p< 0.05). There were no significant relationships between celiac positive serology in children with dental caries, the number of decayed teeth, and breastfeeding (p> 0.05).

Conclusion: The present study showed that dental caries, might be a red flag indicating possible celiac disease and prevent its complications. On the other hand, pediatricians and dentists should be aware of the oral symptoms of celiac disease. Further studies are needed to plan screening for children with celiac disease.

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龋齿儿童乳糜泻的血清学研究。

背景:乳糜泻是一种常见的胃肠道自身免疫性疾病。研究表明，乳糜泻患者中蛀牙的患病率很高。本研究旨在评估患有龋齿的儿童乳糜泻的血清学。方法:以3 ~ 12岁就诊的牙釉质龋患儿为研究对象。通过测定血清IgA水平和抗TTG(抗TTG (IgA))抗体来评估乳糜泻。然后，通过分析收集到的数据，探讨乳糜泻在龋齿儿童中的患病率及其与各变量的关系。结果:本组龋病患儿120例，其中女孩56例(46.7%)，男孩64例(53.3%)。研究人群乳糜泻血清学阳性率为14例(11.6%)。本研究结果显示，母亲受教育程度、性别和居住地与乳糜泻有显著相关(p< 0.05)。乳糜泻阳性血清学与龋齿数、母乳喂养无显著相关性(p> 0.05)。结论:目前的研究表明，龋齿可能是乳糜泻的一个危险信号，可以预防其并发症。另一方面，儿科医生和牙医应该了解乳糜泻的口腔症状。需要进一步的研究来计划对患有乳糜泻的儿童进行筛查。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Human Antibodies Medicine-Immunology and Allergy

CiteScore

3.50

自引率

0.00%

发文量

期刊介绍： Human Antibodies is an international journal designed to bring together all aspects of human hybridomas and antibody technology under a single, cohesive theme. This includes fundamental research, applied science and clinical applications. Emphasis in the published articles is on antisera, monoclonal antibodies, fusion partners, EBV transformation, transfections, in vitro immunization, defined antigens, tissue reactivity, scale-up production, chimeric antibodies, autoimmunity, natural antibodies/immune response, anti-idiotypes, and hybridomas secreting interesting growth factors. Immunoregulatory molecules, including T cell hybridomas, will also be featured.