Anti-A₁Le^b: a mind boggler.

Q4 Medicine Immunohematology Pub Date : 2021-06-01 DOI:10.21307/immunohematology-2021-010

A Gupta, K Chaudhary, S Asati, B Kakkar

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Abstract

The Lewis blood group system is unique because antigens are neither alleles of the same gene nor are they synthesized by red blood cells (RBCs); rather, they are adsorbed onto the RBC membrane from plasma as glycolipids. Antibodies against Lewis antigens are predominantly naturally occurring immunoglobulin (Ig)M type that sometimes react at 37°C and the antihuman globulin phase. Lewis compound antigens, ALe^b and BLe^b, have been described that were confirmed because of the presence of antibodies against them. These compound antigens are the result of an interaction between ABO, H, SE, and LE genes.

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反a1leb:一个令人难以置信的人。

刘易斯血型系统是独特的，因为抗原既不是同一基因的等位基因，也不是由红细胞合成的;相反，它们以糖脂的形式从血浆中吸附到红细胞膜上。针对Lewis抗原的抗体主要是天然存在的免疫球蛋白(Ig)M型，有时在37°C和抗人球蛋白期发生反应。Lewis复合抗原，ALeb和BLeb，已经被描述，因为存在针对它们的抗体而被证实。这些复合抗原是ABO、H、SE和LE基因相互作用的结果。刘易斯血型系统是独特的，因为抗原既不是同一基因的等位基因，也不是由红细胞合成的;相反，它们以糖脂的形式从血浆中吸附到红细胞膜上。针对Lewis抗原的抗体主要是天然存在的免疫球蛋白(Ig)M型，有时在37°C和抗人球蛋白期发生反应。Lewis复合抗原，ALeb和BLeb，已经被描述，因为存在针对它们的抗体而被证实。这些复合抗原是ABO、H、SE和LE基因相互作用的结果。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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