International multidisciplinary team discussions on the diagnosis of idiopathic non-specific interstitial pneumonia and the development of connective tissue disease.

IF 1.8 Q3 RESPIRATORY SYSTEM European Clinical Respiratory Journal Pub Date : 2021-06-10 DOI:10.1080/20018525.2021.1933878
Janne Møller, Alan Altraja, Tone Sjåheim, Finn Rasmussen, Line Bille Madsen, Elisabeth Bendstrup
{"title":"International multidisciplinary team discussions on the diagnosis of idiopathic non-specific interstitial pneumonia and the development of connective tissue disease.","authors":"Janne Møller,&nbsp;Alan Altraja,&nbsp;Tone Sjåheim,&nbsp;Finn Rasmussen,&nbsp;Line Bille Madsen,&nbsp;Elisabeth Bendstrup","doi":"10.1080/20018525.2021.1933878","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Idiopathic Non-Specific Interstitial Pneumonia (iNSIP) is a rare interstitial lung disease, diagnosed, by definition, on the basis of a multidisciplinary team discussion (MDD). Association with an autoimmune background has been suggested in iNSIP.</p><p><strong>Aims: </strong>To test the feasibility of conducting a multinational MDD to review the diagnosis in iNSIP cases and to estimate the emergence of connective tissue disease (CTD) during follow-up.</p><p><strong>Methods: </strong>Investigators from three expert centers (Denmark, Estonia and Norway) met and discussed cases of biopsy-proven iNSIP at an international MDD. The cases were previously diagnosed at a national level between 2004 and 2014. Based on clinical, radiographic and pathological data, the diagnosis of iNSIP was re-evaluated and a consensus diagnosis was made. Cases incompatible with iNSIP were excluded. Relevant data were registered comprising any development of CTD.</p><p><strong>Results: </strong>In total, 31 cases were discussed and 23 patients were included with a diagnosis of iNSIP. The mean follow-up time was 57 months. None of the patients developed CTD according to the rheumatologic criteria during the follow up period. Four patients (17.4%) met the criteria for interstitial pneumonia with autoimmune features.</p><p><strong>Conclusion: </strong>We found that an international MDD was a feasible and valuable tool in the retrospective diagnostic evaluation of iNSIP. Diagnosis was changed in a statistically significant number of patients by our international MDD team. None of the patients developed CTD during follow-up.</p>","PeriodicalId":11872,"journal":{"name":"European Clinical Respiratory Journal","volume":null,"pages":null},"PeriodicalIF":1.8000,"publicationDate":"2021-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/20018525.2021.1933878","citationCount":"1","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"European Clinical Respiratory Journal","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1080/20018525.2021.1933878","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"RESPIRATORY SYSTEM","Score":null,"Total":0}
引用次数: 1

Abstract

Background: Idiopathic Non-Specific Interstitial Pneumonia (iNSIP) is a rare interstitial lung disease, diagnosed, by definition, on the basis of a multidisciplinary team discussion (MDD). Association with an autoimmune background has been suggested in iNSIP.

Aims: To test the feasibility of conducting a multinational MDD to review the diagnosis in iNSIP cases and to estimate the emergence of connective tissue disease (CTD) during follow-up.

Methods: Investigators from three expert centers (Denmark, Estonia and Norway) met and discussed cases of biopsy-proven iNSIP at an international MDD. The cases were previously diagnosed at a national level between 2004 and 2014. Based on clinical, radiographic and pathological data, the diagnosis of iNSIP was re-evaluated and a consensus diagnosis was made. Cases incompatible with iNSIP were excluded. Relevant data were registered comprising any development of CTD.

Results: In total, 31 cases were discussed and 23 patients were included with a diagnosis of iNSIP. The mean follow-up time was 57 months. None of the patients developed CTD according to the rheumatologic criteria during the follow up period. Four patients (17.4%) met the criteria for interstitial pneumonia with autoimmune features.

Conclusion: We found that an international MDD was a feasible and valuable tool in the retrospective diagnostic evaluation of iNSIP. Diagnosis was changed in a statistically significant number of patients by our international MDD team. None of the patients developed CTD during follow-up.

Abstract Image

Abstract Image

Abstract Image

查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
国际多学科小组讨论特发性非特异性间质性肺炎的诊断和结缔组织病的发展。
背景:特发性非特异性间质性肺炎(iNSIP)是一种罕见的间质性肺病,根据多学科团队讨论(MDD)的定义进行诊断。iNSIP中已提出与自身免疫背景有关。目的:测试进行多国MDD检查iNSIP病例诊断的可行性,并评估随访期间结缔组织疾病(CTD)的出现。方法:来自三个专家中心(丹麦、爱沙尼亚和挪威)的研究人员在国际MDD。这些病例之前是在2004年至2014年期间在国家层面诊断的。根据临床、放射学和病理学数据,对iNSIP的诊断进行了重新评估,并达成了一致诊断。排除与iNSIP不兼容的病例。相关数据包括CTD的任何发展。结果:总共讨论了31例病例,23名患者被诊断为iNSIP。平均随访时间57个月。在随访期间,根据风湿病标准,没有一名患者出现CTD。4名患者(17.4%)符合具有自身免疫特征的间质性肺炎的标准。结论:我们发现国际MDD在iNSIP的回顾性诊断评估中是一种可行且有价值的工具。我们的国际MDD团队在统计上显著数量的患者中改变了诊断。随访期间,没有患者出现CTD。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 去求助
来源期刊
CiteScore
3.80
自引率
0.00%
发文量
15
审稿时长
16 weeks
期刊最新文献
Factors behind favorable long-term lung cancer survival in Norway compared to Denmark: a retrospective cohort study. Socioeconomic status and emergency department visits in adults with a history of severe childhood asthma: a register-based study. Comorbid allergy and rhinitis and patient-related outcomes in asthma and COPD: a cross-sectional study. Lung function measurements in the Greenlandic Inuit population: results from the Greenlandic health survey 2017-2019. Asthma severity: the patient's point of view.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1