Impact of Confinement on the Burden of Caregivers of Patients with the Behavioral Variant of Frontotemporal Dementia and Alzheimer Disease during the COVID-19 Crisis in France.

IF 1.4 Q4 CLINICAL NEUROLOGY Dementia and Geriatric Cognitive Disorders Extra Pub Date : 2020-11-12 eCollection Date: 2020-09-01 DOI:10.1159/000511416
Claire Boutoleau-Bretonnière, Hélène Pouclet-Courtemanche, Aurélie Gillet, Amélie Bernard, Anne-Laure Deruet, Inès Gouraud, Estelle Lamy, Aurélien Mazoué, Laëtitia Rocher, Cédric Bretonnière, Mohamad El Haj
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引用次数: 23

Abstract

Introduction: The clinical presentation of the behavioral variant of frontotemporal dementia (bvFTD) differs from that of Alzheimer disease (AD), with major impairments in behavioral functions in bvFTD and cognitive impairment in AD. Both behavioral disturbances in bvFTD and cognitive impairment in AD contribute to caregiver burden.

Objective: To investigate the impact of home confinement during the COVID-19 crisis on the burden of caregivers of bvFTD or AD patients.

Methods: During the COVID-19 lockdown in France, neurologists and neuropsychologists from the Memory Center of Nantes Hospital conducted teleconsultations for 38 AD patients and 38 bvFTD patients as well as for their caregivers. During these consultations, caregivers were invited to rate the change in their burden during home confinement. They were also invited to rate behavioral or emotional changes in the patients during, compared with before, the confinement.

Results: Twenty-two bvFTD caregivers and 14 AD caregivers experienced an increase in burden. For bvFTD caregivers, this increased burden occurred regardless of behavioral changes, while AD caregivers experienced an increased burden related to changes in patients' neuropsychiatric symptoms. Among the whole cohort, 2 factors were associated with increased caregiver burden: behavioral change and bvFTD.

Conclusion: The results demonstrate that during home confinement in the COVID-19 crisis, neuropsychiatric symptoms were the core factor that impacted caregiver burden in different ways depending on the disease.

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COVID-19危机期间,法国禁闭对额颞叶痴呆和阿尔茨海默病行为变异患者照顾者负担的影响
前言:额颞叶痴呆(bvFTD)行为变异的临床表现不同于阿尔茨海默病(AD), bvFTD主要表现为行为功能障碍,AD表现为认知障碍。bvFTD患者的行为障碍和AD患者的认知障碍都加重了照顾者的负担。目的:探讨COVID-19危机期间居家隔离对bvFTD或AD患者护理人员负担的影响。方法:在法国COVID-19封锁期间,南特医院记忆中心的神经科医生和神经心理学家对38名AD患者和38名bvFTD患者及其护理人员进行了远程会诊。在这些咨询中,护理人员被邀请对其在家坐月子期间的负担变化进行评估。他们还被邀请对患者在禁闭期间的行为或情绪变化进行评分,并与禁闭前进行比较。结果:22名bvFTD护理人员和14名AD护理人员的负担增加。对于bvFTD护理人员,无论行为改变如何,这种增加的负担都会发生,而AD护理人员的负担增加与患者神经精神症状的变化有关。在整个队列中,2个因素与照顾者负担增加有关:行为改变和bvFTD。结论:新冠肺炎居家隔离期间,神经精神症状是影响照顾者负担的核心因素,不同疾病的影响方式不同。
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来源期刊
Dementia and Geriatric Cognitive Disorders Extra
Dementia and Geriatric Cognitive Disorders Extra Medicine-Psychiatry and Mental Health
CiteScore
4.30
自引率
0.00%
发文量
18
审稿时长
9 weeks
期刊介绍: This open access and online-only journal publishes original articles covering the entire spectrum of cognitive dysfunction such as Alzheimer’s and Parkinson’s disease, Huntington’s chorea and other neurodegenerative diseases. The journal draws from diverse related research disciplines such as psychogeriatrics, neuropsychology, clinical neurology, morphology, physiology, genetic molecular biology, pathology, biochemistry, immunology, pharmacology and pharmaceutics. Strong emphasis is placed on the publication of research findings from animal studies which are complemented by clinical and therapeutic experience to give an overall appreciation of the field. Dementia and Geriatric Cognitive Disorders Extra provides additional contents based on reviewed and accepted submissions to the main journal Dementia and Geriatric Cognitive Disorders Extra .
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