Detection of Anti-Toxoplasma gondii IgG and IgM Antibodies and Associated Risk Factors during Pregnancy in Southwest Iran.

Q2 Medicine Infectious Diseases in Obstetrics and Gynecology Pub Date : 2021-05-27 eCollection Date: 2021-01-01 DOI:10.1155/2021/5547667

Shahrzad Soltani, Ali Dalir Ghaffari, Mehdi Sagha Kahvaz, Mohamad Sabaghan, Marzieh Pashmforosh, Masoud Foroutan

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引用次数: 6

Abstract

Background: This research was aimed at evaluating the seroprevalence of acute and chronic Toxoplasma gondii (T. gondii) infection in pregnant women and related risk factors in southwest Iran.

Methods: In this cross-sectional study, eighty-eight pregnant women were included from October 2019 to December 2019. The presence of anti-T. gondii IgM and IgG antibodies was measured using the enzyme-linked immunosorbent assay (ELISA). In addition, a questionnaire consisting of demographic information was completed for each subject.

Results: The overall seroprevalence of T. gondii infection was estimated to be 34.09% (30/88). Of these, 1 (1.13%) and 29 (32.95%) samples were found positive for IgM and IgG, respectively. Regarding the risk factors, the consumption of raw/undercooked meat (P value = 0.007) and history of abortion (P value = 0.017) were significantly associated with IgG seroprevalence in pregnant women.

Conclusion: The results showed that the pregnant women of southwest Iran might be moderately exposed to T. gondii. Since the risk of acute T. gondii infection in this susceptible group is very important, regular screening tests to diagnose the infection are recommended before pregnancy.

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伊朗西南部孕妇抗刚地弓形虫IgG和IgM抗体检测及相关危险因素

背景:本研究旨在评估伊朗西南地区孕妇急性和慢性刚地弓形虫(T. gondii)感染的血清阳性率及其相关危险因素。方法:在本横断面研究中，于2019年10月至2019年12月纳入88名孕妇。anti-T的存在。采用酶联免疫吸附试验(ELISA)检测弓形虫IgM和IgG抗体。此外，还为每个对象填写了一份人口统计资料调查表。结果:总体血清弓形虫感染率为34.09%(30/88)。其中IgM阳性1份(1.13%)，IgG阳性29份(32.95%)。在危险因素方面，食用生/未煮熟的肉类(P值= 0.007)和流产史(P值= 0.017)与孕妇IgG血清阳性率显著相关。结论:伊朗西南地区孕妇可能存在中等程度的弓形虫暴露。由于这一易感人群急性弓形虫感染的风险非常重要，因此建议在怀孕前进行定期筛查以诊断感染。

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来源期刊

Infectious Diseases in Obstetrics and Gynecology Medicine-Obstetrics and Gynecology

CiteScore

3.80

自引率

0.00%

发文量

审稿时长

12 weeks

期刊介绍： Infectious Diseases in Obstetrics and Gynecology aims to disseminate new and important information to clinicians and other health care providers, scientists, and researchers involved in the study or treatment of infectious diseases, especially those affecting the female patient. Its ultimate aim is to advance knowledge and encourage research, thereby improving the prevention or diagnosis and treatment of patients affected by such diseases.