New Potential Options for SBRT in Pancreatic Cancer.

Cancer medicine journal Pub Date : 2021-03-01 Epub Date: 2021-02-18
Maged Ghaly, Emile Gogineni, Joseph Herman, Muhammad W Saif
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Abstract

Stereotactic body radiotherapy (SBRT) is an emerging treatment option for patients with pancreatic cancer, as it can provide a therapeutic benefit with significant advantages for patients' quality of life over standard conventional chemoradiation (CRT). The objective of this review is to present alternative clinical settings in which SBRT may benefit patients with pancreatic cancer. These include palliation of pain, elderly patients who are not surgical candidates, local therapy in oligometastatic cases and salvaging local failures after surgery or external beam radiation. We will review these individually and provide supporting literature for each.

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胰腺癌SBRT治疗的潜在新选择
立体定向放射治疗(SBRT)是胰腺癌患者的一种新兴治疗选择,因为它可以提供治疗效益,对患者的生活质量比标准常规放化疗(CRT)有显着优势。本综述的目的是提出可选择的临床环境,其中SBRT可能使胰腺癌患者受益。这些措施包括减轻疼痛,不适合手术的老年患者,对少转移病例进行局部治疗,以及在手术或外部放射治疗后挽救局部失败。我们将单独审查这些,并为每一个提供支持文献。
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