Human Health Assessment of Sixteen Priority Polycyclic Aromatic Hydrocarbons in Contaminated Soils of Northwestern Algeria.

IF 2.4 Q1 Medicine Journal of Health and Pollution Pub Date : 2021-08-17 eCollection Date: 2021-09-01 DOI:10.5696/2156-9614-11.31.210914
Ahmed Halfadji, Mohamed Naous, Farida Bettiche, Abdelkrim Touabet
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引用次数: 6

Abstract

Background: Polycyclic aromatic hydrocarbons (PAHs) are ubiquitous environmental organic contaminants generated by incomplete combustion of organic materials that are widely distributed in soils.

Objectives: This study represents the first attempt to examine the health toxicity of 16 detected PAHs in contaminated soil, via different exposure pathways to populations in northwestern Algeria.

Methods: The toxicity equivalency quotients (TEQ) of PAHs were evaluated. The carcinogenic risk assessment of incremental lifetime cancer risk (ILCR) from ingestion, inhalation, and dermal exposure pathways to each PAH in soil are described.

Results: Incremental lifetime cancer risk values were in the upper limit of the tolerable range (10-6-10-4) for adults and children. The total cancer risk of PAH-contaminated soils for children, adolescents and adults was 2.48×10-5, 2.04×10-5 and 3.12×10-5mg.kg-1d-1, respectively. The highest potential cancer risks were identified for adults and children, with adolescents having the lowest risks. Across exposure pathways, the dermal contact and ingestion pathways had the greatest contributions to the carcinogenic risk of human exposure to PAHs.

Conclusions: Further research and guidelines are needed for risk assessments of PAHs in agricultural, residential/urban, and industrial areas, and further risk assessments should include risks posed by exposure through air.

Competing interests: The authors declare no competing financial interests.

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阿尔及利亚西北部污染土壤中16种优先多环芳烃的人体健康评价
背景:多环芳烃(Polycyclic aromatic hydrocarbons, PAHs)是一种普遍存在的环境有机污染物,广泛分布于土壤中。目的:本研究首次尝试通过阿尔及利亚西北部人群的不同接触途径,检查受污染土壤中检测到的16种多环芳烃的健康毒性。方法:测定多环芳烃的毒性当量商(TEQ)。从摄入、吸入和皮肤暴露途径对土壤中每一种多环芳烃的增量终生癌症风险(ILCR)进行致癌风险评估。结果:成人和儿童终生癌症风险增量值均在可容忍范围的上限(10-6-10-4)。多环芳烃污染土壤对儿童、青少年和成人的总致癌风险分别为2.48×10-5、2.04×10-5和3.12×10-5mg。分别kg-1d-1。成人和儿童的潜在癌症风险最高,青少年的风险最低。在接触途径中,皮肤接触和摄入途径对人体接触多环芳烃的致癌风险贡献最大。结论:农业、住宅/城市和工业地区多环芳烃的风险评估需要进一步的研究和指南,进一步的风险评估应包括通过空气暴露的风险。利益竞争:作者声明没有经济利益竞争。
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Journal of Health and Pollution
Journal of Health and Pollution Medicine-Public Health, Environmental and Occupational Health
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审稿时长
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期刊介绍: The Journal of Health and Pollution (JH&P) was initiated with funding from the European Union and World Bank and continues to be a Platinum Open Access Journal. There are no publication or viewing charges. That is, there are no charges to readers or authors. Upon peer-review and acceptance, all articles are made available online. The high-ranking editorial board is comprised of active members who participate in JH&P submissions and editorial policies. The Journal of Health and Pollution welcomes manuscripts based on original research as well as findings from re-interpretation and examination of existing data. JH&P focuses on point source pollution, related health impacts, environmental control and remediation technology. JH&P also has an interest in ambient and indoor pollution. Pollutants of particular interest include heavy metals, pesticides, radionuclides, dioxins, polychlorinated biphenyls (PCBs), polycyclic aromatic hydrocarbons (PAHs), volatile organic compounds (VOCs), air particulates (PM10 and PM2.5), and other severe and persistent toxins. JH&P emphasizes work relating directly to low and middle-income countries, however relevant work relating to high-income countries will be considered on a case-by-case basis.
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