Qi Ye, Bingo Wing-Kuen Ling, Nuo Xu, Yuxin Lin, Lingyue Hu
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引用次数: 2
Abstract
Prehypertension is a new risky disease defined in the seventh report issued by the Joint National Commission. Hence, detecting prehypertension in time plays a very important role in protecting human lives. This study proposes a method for categorising blood pressure values into two classes, namely the class of healthy blood pressure values and the class of prehypertension blood pressure values, as well as estimating the blood pressure values continuously only by employing photoplethysmograms. First, the denoising of photoplethysmograms is performed via a discrete cosine transform approach. Then, the features of the photoplethysmograms in both the time domain and the frequency domain are extracted. Next, the feature vectors are categorised into the two classes of blood pressure values by a multi-model fusion of the classifiers. Here, the support vector machine, the random forest and the K-nearest neighbour classifier are employed for performing the fusion. There are two types of blood pressure values. They are the systolic blood pressure values and the diastolic blood pressure values. For each class and each type of blood pressure values, support vector regression is used to estimate the blood pressure values. Since different classes and different types of blood pressure values are considered separately, the proposed method achieves an accurate estimation. The computed numerical simulation results show that the proposed method based on the multi-model fusion of the classifiers achieves both higher classification accuracy and higher regression accuracy than the individual classification methods.
期刊介绍:
IET Systems Biology covers intra- and inter-cellular dynamics, using systems- and signal-oriented approaches. Papers that analyse genomic data in order to identify variables and basic relationships between them are considered if the results provide a basis for mathematical modelling and simulation of cellular dynamics. Manuscripts on molecular and cell biological studies are encouraged if the aim is a systems approach to dynamic interactions within and between cells.
The scope includes the following topics:
Genomics, transcriptomics, proteomics, metabolomics, cells, tissue and the physiome; molecular and cellular interaction, gene, cell and protein function; networks and pathways; metabolism and cell signalling; dynamics, regulation and control; systems, signals, and information; experimental data analysis; mathematical modelling, simulation and theoretical analysis; biological modelling, simulation, prediction and control; methodologies, databases, tools and algorithms for modelling and simulation; modelling, analysis and control of biological networks; synthetic biology and bioengineering based on systems biology.