Reproduction-Associated Hormones and Adult Hippocampal Neurogenesis.

IF 3 4区 医学 Q2 NEUROSCIENCES Neural Plasticity Pub Date : 2021-09-10 eCollection Date: 2021-01-01 DOI:10.1155/2021/3651735
Lily Wan, Rou-Jie Huang, Zhao-Hui Luo, Jiao-E Gong, Aihua Pan, Jim Manavis, Xiao-Xin Yan, Bo Xiao
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Abstract

The levels of reproduction-associated hormones in females, such as estrogen, progesterone, prolactin, and oxytocin, change dramatically during pregnancy and postpartum. Reproduction-associated hormones can affect adult hippocampal neurogenesis (AHN), thereby regulating mothers' behavior after delivery. In this review, we first briefly introduce the overall functional significance of AHN and the methods commonly used to explore this front. Then, we attempt to reconcile the changes of reproduction-associated hormones during pregnancy. We further update the findings on how reproduction-related hormones influence adult hippocampal neurogenesis. This review is aimed at emphasizing a potential role of AHN in reproduction-related brain plasticity and its neurobiological relevance to motherhood behavior.

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生殖相关激素与成年海马神经发生
雌激素、孕酮、催乳素和催产素等女性生殖相关激素的水平在孕期和产后会发生显著变化。生殖相关激素可影响成年海马神经发生(AHN),从而调节母亲产后的行为。在这篇综述中,我们首先简要介绍了 AHN 的整体功能意义以及探索这一领域的常用方法。然后,我们试图调和孕期生殖相关激素的变化。我们进一步更新了生殖相关激素如何影响成人海马神经发生的研究结果。本综述旨在强调 AHN 在与生殖相关的大脑可塑性中的潜在作用及其与母亲行为的神经生物学相关性。
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来源期刊
Neural Plasticity
Neural Plasticity NEUROSCIENCES-
CiteScore
6.80
自引率
0.00%
发文量
77
审稿时长
16 weeks
期刊介绍: Neural Plasticity is an international, interdisciplinary journal dedicated to the publication of articles related to all aspects of neural plasticity, with special emphasis on its functional significance as reflected in behavior and in psychopathology. Neural Plasticity publishes research and review articles from the entire range of relevant disciplines, including basic neuroscience, behavioral neuroscience, cognitive neuroscience, biological psychology, and biological psychiatry.
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