V.I.T.A.M. in COVID 19: A Systematic Approach to a Global Pandemic.

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY Accounts of Chemical Research Pub Date : 2021-10-04 eCollection Date: 2021-01-01 DOI:10.1177/11795484211047432

Siva Naga S Yarrarapu, Pankaj Bansal, David Abia-Trujillo, Austin Cusick, Megan Melody, Varun Moktan, Andrea Rivero, Tara J Brigham, Claudia Libertin, Lisa Brumble, J O'brein Jennifer, Augustine Lee, Torp Klaus, Christan Santos, Candido Rivera, Jason Siegel, Pramod Guru, Pablo Moreno Franco, Devang Sanghavi

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Abstract

Introduction: In the unprecedented era of COVID-19, ongoing research and evolution of evidence has led to ever-changing guidelines for clinical monitoring and therapeutic options. Formulating treatment protocols requires the understanding and application of the evolving research.

Objective: The primary objective of this study is to present a systematic evidence-based approach to synthesize the necessary data in order to optimize the management of COVID-19.

Methods: At Mayo Clinic Florida, we developed a multidisciplinary centralized COVID Treatment Review Panel (TRP) of expert pulmonologists, intensivists, infectious disease specialists, anesthesiologists, hematologists, rheumatologists, and hospitalists that in real-time reviews the latest evidence in peer-reviewed journals, the available clinical trials, and help guide the rapid application of therapeutics or interventions to the patient and the bedside provider.

Results/conclusions: The multi-disciplinary team approach of synthesizing clinical data and coordinating care is effective in responding to rapidly evolving and changing evidence. Systematic data collection and evidence-based treatment algorithms enable physicians to rapidly translate the current literature to clinical practice, and improve care and outcomes of patients.

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COVID - 19中的V.I.T.A.M.:全球大流行的系统方法。

在前所未有的COVID-19时代，持续的研究和证据的演变导致临床监测指南和治疗方案不断变化。制定治疗方案需要理解和应用不断发展的研究。目的:本研究的主要目的是提出一种系统的循证方法，综合必要的数据，以优化COVID-19的管理。方法:在佛罗里达州梅奥诊所，我们建立了一个多学科集中的COVID治疗审查小组(TRP)，由肺科专家、重症医师、传染病专家、麻醉科专家、血液学家、风湿病学家和医院专家组成，实时审查同行评议期刊中的最新证据、可用的临床试验，并帮助指导治疗方法或干预措施快速应用于患者和床边提供者。结果/结论:综合临床数据和协调护理的多学科团队方法在应对快速发展和变化的证据方面是有效的。系统的数据收集和循证治疗算法使医生能够迅速将当前文献转化为临床实践，并改善患者的护理和预后。

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.