[Localized prostate cancer].

4区 医学 Q3 Medicine Pathologe Pub Date : 2021-11-01 Epub Date: 2021-10-14 DOI:10.1007/s00292-021-00997-8
V W Sailer, S Perner, P Wild, J Köllermann
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引用次数: 0

Abstract

Prostate cancer is the most prevalent noncutaneous cancer in men. The Gleason grading is considered to be the strongest prognostic parameter regarding progression-free survival and overall survival. The original grading system has been modified during the last decade resulting in a more precise prognostic tool. The pretreatment Gleason score guides clinical management and is a key component in S3 guidelines for prostate cancer. In addition to Gleason score several other histologic findings in prostate needle biopsy influence patient management. In this second part of our CME series about prostate cancer, we will discuss the diagnosis of prostate cancer and current guidelines for reporting prostate cancer. In addition, we will highlight prostate lesions of urothelial origin and neuroendocrine prostate cancer as well as prognostic biomarkers.

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[局限性前列腺癌]。
前列腺癌是男性中最常见的非皮肤癌症。Gleason分级被认为是关于无进展生存期和总生存期的最强预后参数。在过去十年中,原有的分级系统已经过修改,形成了一种更精确的预测工具。预处理Gleason评分指导临床管理,是前列腺癌S3指南的关键组成部分。除了Gleason评分外,前列腺穿刺活检的其他组织学结果也会影响患者的治疗。在我们关于前列腺癌的CME系列的第二部分,我们将讨论前列腺癌的诊断和目前报告前列腺癌的指南。此外,我们将强调尿路上皮起源的前列腺病变和神经内分泌前列腺癌以及预后生物标志物。
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来源期刊
Pathologe
Pathologe 医学-病理学
CiteScore
1.50
自引率
0.00%
发文量
40
审稿时长
4-8 weeks
期刊介绍: Der Pathologe is an internationally recognized journal and combines practical relevance with scientific competence. The journal informs all pathologists working on departments and institutes as well as morphologically interested scientists about developments in the field of pathology. The journal serves both the scientific exchange and the continuing education of pathologists. Comprehensive reviews on a specific topical issue focus on providing evidenced based information under consideration of practical experience. Freely submitted original papers allow the presentation of important clinical studies and serve the scientific exchange.
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