Impact of SARS-CoV-2 infection on oral carcinoma patients.

Q2 Medicine Journal of Buon Pub Date : 2021-09-01

Vasileios Ragos, Maria Adamopoulou, Arezina Manoli, Spyros Katsinis, Sotirios Papouliakos, Odysseas Dimas, Evangelos Tsiambas, Dimitrios Roukas, George Papanastasiou, Despoina Spyropoulou, Loukas Manaios, Asimakis Asimakopoulos, Nicholaos Mastronikolis, Fragiski Anthouli Anagnostopoulou

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引用次数: 0

Abstract

Coronavirus-related Severe Acute Respiratory Syndrome (SARS-CoV) in 2002/2003, Middle-East Respiratory Syndrome (MERS-Cov) in 2012/2013, and especially the current 2019/2020 Severe Acute Respiratory Syndrome-2 (SARS-CoV-2) tested the national health systems' endurance worldwide. In order to fight this emergency situation, a variety of pharmaceutical companies focused on the design and development of efficient vaccines that are considered necessary for providing a level of normalization in totally affected human social-economical activity worldwide. COVID-19 led to an increased uncertainty in the field of oncological patients' management disrupting the normal conditions of therapeutic and monitoring procedures. In the current article, we explored the impact of SARS-CoV-2 infection on oral carcinoma patients. We observed COVD-19 pandemic negatively affects the normality regarding early diagnosis and optimal management (surgical operation, post-operational follow up/monitoring) in HNSCC/OSCC patients. Understanding the involvement of SARS-CoV-2 in the progression of malignancies is the first critical step for targeting the virus by efficient monoclonal antibodies and vaccines.

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SARS-CoV-2感染对口腔癌患者的影响

2002/2003年的冠状病毒相关的严重急性呼吸综合征(SARS-CoV)， 2012/2013年的中东呼吸综合征(MERS-Cov)，特别是目前的2019/2020年严重急性呼吸综合征-2 (SARS-CoV-2)，考验了世界各国卫生系统的忍耐力。为了应对这一紧急情况，各种制药公司集中精力设计和开发有效的疫苗，这些疫苗被认为是使全世界受到完全影响的人类社会经济活动恢复正常水平所必需的。COVID-19导致肿瘤患者管理领域的不确定性增加，扰乱了治疗和监测程序的正常条件。在本文中，我们探讨了SARS-CoV-2感染对口腔癌患者的影响。我们观察到covid -19大流行对HNSCC/OSCC患者的早期诊断和最佳治疗(手术、术后随访/监测)的正常性产生负面影响。了解SARS-CoV-2在恶性肿瘤进展中的作用是利用有效的单克隆抗体和疫苗靶向该病毒的关键第一步。

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来源期刊

Journal of Buon 医学-肿瘤学

自引率

0.00%

发文量

审稿时长

4-8 weeks

期刊介绍： JBUON aims at the rapid diffusion of scientific knowledge in Oncology. Its character is multidisciplinary, therefore all aspects of oncologic activities are welcome including clinical research (medical oncology, radiation oncology, surgical oncology, nursing oncology, psycho-oncology, supportive care), as well as clinically-oriented basic and laboratory research, cancer epidemiology and social and ethical aspects of cancer. Experts of all these disciplines are included in the Editorial Board. With a rapidly increasing body of new discoveries in clinical therapeutics, the molecular mechanisms that contribute to carcinogenesis, advancements in accurate and early diagnosis etc, JBUON offers a free forum for clinicians and basic researchers to make known promptly their achievements around the world. With this aim JBUON accepts a broad spectrum of articles such as editorials, original articles, reviews, special articles, short communications, commentaries, letters to the editor and correspondence among authors and readers. JBUON keeps the characteristics of its former paper print edition and appears as a bimonthly e-published journal with continuous volume, issue and page numbers.