The Co-Occurrence of Autism Spectrum Disorder and Cerebral Palsy and Associated Comorbid Conditions in Children and Adolescents.

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY Accounts of Chemical Research Pub Date : 2022-07-01 Epub Date: 2021-12-16 DOI:10.1080/17518423.2021.2011456

Geraldine Leader, Aisling Mooney, June L Chen, Sally Whelan, Katie Naughton, Leanne Maher, Arlene Mannion

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Abstract

Background: Comorbidity is the co-occurrence of two or more disorders in the same person.

Aim: This study investigated the frequency of comorbid conditions, in children and adolescents, with autism spectrum disorder (ASD), cerebral palsy (CP), and a comorbid diagnosis of ASD and CP.

Method: Ninety-six children and adolescents with ASD, CP, and both ASD and CP aged between 4 and 18 years participated in this study. Parents completed the Gastrointestinal Symptom Inventory, Children's Sleep Habits Questionnaire, Child Behavior Checklist, Social Communication Questionnaire, and the Vineland Adaptive Behavior Scales.

Results: Results of ANOVA analyses revealed significant group differences in sleep problems, social communication difficulties, and adaptive behavior. Regression analysis found that the presence of an intellectual disability significantly predicted levels of adaptive behavior.

Conclusion: This research demonstrated the importance of studying comorbidities in children and adolescents with CP alone, ASD alone, and combined ASD and CP.

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儿童和青少年自闭症谱系障碍与脑瘫的共发及相关合并症

背景:合并症是指同一个人同时出现两种或两种以上的疾病。目的:探讨自闭症谱系障碍(ASD)、脑瘫(CP)患儿和青少年共病的发生率，以及ASD和CP的合并症诊断。方法:96名年龄在4 ~ 18岁的ASD、CP、ASD和CP兼有的患儿和青少年参加本研究。家长完成胃肠症状量表、儿童睡眠习惯问卷、儿童行为检查表、社会沟通问卷和Vineland适应行为量表。结果:方差分析结果显示，在睡眠问题、社会沟通困难和适应行为方面，组间存在显著差异。回归分析发现，智力残疾的存在显著地预测了适应行为的水平。结论:本研究表明了研究儿童和青少年单独患有CP、单独患有ASD以及ASD和CP合并的合并症的重要性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.

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