MicroRNAs: Beyond Post-transcriptional Regulation of mRNAs.

Cervantes-Ayala Andrea Viridiana, Velázquez-Flores Miguel Ángel, Ruiz Esparza-Garrido Ruth
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Abstract

MicroRNAs (miRNAs), small non-coding RNAs, participate in the transcriptional and post-transcriptional regulation of eukaryotic genes, and are potential biomarkers for diseases. Mature miRNAs can be located in both the nucleus and cytoplasm, where they perform their regulatory function. The discovery of new miRNAs and the identification of their targets and functions are fundamental to understanding the biological processes regulated by them, as well as the role they play in diseases. This present study researched miRNAs function at nuclear level and as circulating molecules.

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MicroRNAs:超越mrna的转录后调控。
MicroRNAs (miRNAs)是一种小的非编码rna,参与真核生物基因的转录和转录后调控,是潜在的疾病生物标志物。成熟的mirna可以位于细胞核和细胞质中,并在其中发挥其调节功能。新mirna的发现及其靶点和功能的鉴定是了解其调控的生物过程及其在疾病中的作用的基础。本研究主要研究了miRNAs在核水平和作为循环分子的功能。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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