Language Development in Sex Chromosome Trisomies: Developmental Profiles at 2 and 4 Years of Age, and Predictive Measures.

IF 1.1 4区 医学 Q4 CLINICAL NEUROLOGY Developmental Neurorehabilitation Pub Date : 2022-07-01 Epub Date: 2022-01-05 DOI:10.1080/17518423.2021.2020925
Elena Capelli, Gaia Silibello, Paola Francesca Ajmone, Elena Altamore, Faustina Lalatta, Paola Giovanna Vizziello, Maria Antonella Costantino, Laura Zampini
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引用次数: 3

Abstract

Purpose: Describing language development in children with sex chromosome trisomies (SCT) and testing the predictive value of early language measures on later outcomes.

Method: Thirteen children with SCT were followed longitudinally. Their developmental profile was assessed, with particular attention to language, at 2 and 4 years. The predictive value of direct (spontaneous speech analysis) and indirect (communicative development inventory) language measures at 2 on performances at 4 was tested.

Results: Language performances at both ages were lower than non-verbal development. At 2, more than 50% of the group produced less than 50 words. At 4, impaired performances were observed in speech sound development and expressive morpho-syntax. Direct measures of Pre-syntactic development predicted later global language outcomes and Sentence Repetition. The number of consonants used at 2 was significantly related to Nonword Repetition at 4.

Conclusions: The study highlights the importance of early detection and careful follow-up for children with SCT.

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性染色体三体的语言发展:2岁和4岁的发展概况及预测措施。
目的:描述性染色体三体(SCT)儿童的语言发展,并测试早期语言测量对后期预后的预测价值。方法:对13例SCT患儿进行纵向随访。在2岁和4岁时对他们的发展状况进行评估,特别关注语言。测试了直接(自发言语分析)和间接(交际发展量表)语言测量在2级时对4级表现的预测价值。结果:两个年龄组的语言表现均低于非语言发展。在2岁时,超过50%的人说的单词少于50个。4岁时,在语音发育和表达形态句法方面表现受损。句法前发展的直接测量预测了后来的整体语言结果和句子重复。2年级的辅音使用数量与4年级的非单词重复显著相关。结论:该研究强调了早期发现和仔细随访儿童SCT的重要性。
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来源期刊
Developmental Neurorehabilitation
Developmental Neurorehabilitation CLINICAL NEUROLOGY-PEDIATRICS
CiteScore
3.10
自引率
0.00%
发文量
27
审稿时长
6-12 weeks
期刊介绍: Developmental Neurorehabilitation aims to enhance recovery, rehabilitation and education of people with brain injury, neurological disorders, and other developmental, physical and intellectual disabilities. Although there is an emphasis on childhood, developmental disability can be considered from a lifespan perspective. This perspective acknowledges that development occurs throughout a person’s life and thus a range of impairments or diseases can cause a disability that can affect development at any stage of life.
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