Spinal Symptoms with Lymphadenoma.

Abstract

IN the course of lymphadenoma involvement of the central nervous system appears to be uncommon. Detailed observation shows however that the incidence of neurological complications is probably higher than is suggested by casual inspection. Ginsburg found clinical evidence of involvement of the brain or spinal cord in ten of 36 cases of Hodgkin's disease. On the other hand, Forrest found that during 20 years at the London Hospital only four cases had shown evidence of involvement of the spinal cord. In one of these cases autopsy revealed syringomyelic cavitation. In a review of 37 cases of Hodgkin's disease with involvement of the central nervous system Johnsson found the brain involved in eight and the spinal cord in 29 cases. Weil, summarizing 46 cases of involvement of the spinal cord in Hodgkin's disease, found dorsal segments affected in 80 per cent., cervical segments in 16 per cent., and lumbosacral segments in 4 per cent. PATHOGENESIS OF SPINAL SYMPTOMS The spinal symptoms and the changes in the spinal cord are produced in various ways.