Acute liver injury and IgG4-related autoimmune pancreatitis following mRNA-based COVID-19 vaccination.

IF 1.2 Q4 GASTROENTEROLOGY & HEPATOLOGY Hepatology Forum Pub Date : 2022-09-23 eCollection Date: 2022-09-01 DOI:10.14744/hf.2022.2022.0019
Ankoor H Patel, Rajan Amin, Alexander T Lalos
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引用次数: 13

Abstract

IgG4-related disease (IgG4-RD) is a fibro-inflammatory disease that can affect multiple organs. Autoimmune pancreatitis type 1 is a manifestation of IgG4-RD and can often mimic tumor-like masses. Autoimmune phenomena following COVID-19 mRNA vaccination are being increasingly reported. Currently, there are no cases in which IgG4-RD involving the hepatobiliary system has been reported following the COVID-19 vaccination. We present the first case of IgG4-RD and AIP type 1 to be associated with the mRNA-based COVID-19 vaccination.

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基于mrna的COVID-19疫苗接种后的急性肝损伤和igg4相关自身免疫性胰腺炎
igg4相关疾病(IgG4-RD)是一种可影响多器官的纤维炎性疾病。自身免疫性胰腺炎1型是IgG4-RD的一种表现,通常可以模拟肿瘤样肿块。COVID-19 mRNA疫苗接种后的自身免疫现象越来越多地被报道。目前,尚未报告在COVID-19疫苗接种后出现涉及肝胆系统的IgG4-RD病例。我们报道了首个与基于mrna的COVID-19疫苗接种相关的IgG4-RD和AIP 1型病例。
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1.90
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12.50%
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