High Dose Intravenous Vitamin C Treatment for Zika Fever.

Michael J Gonzalez, Miguel J Berdiel, Jorgé R Miranda-Massari, Jorgé Duconge, Joshua L Rodríguez-López, Pedro A Adrover-López
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Abstract

The Zika Fever is a viral disease caused by a single-stranded RNA virus from the Flavivirus genus, Flaviviridae family, from the Spondweni group. Its transmission occurs through mosquito vectors, principally Aedes Aegypti. The most common symptoms of Zika are fever, rash, joint pain, and conjunctivitis (red eyes). Other common symptoms include muscle pain and headache. As of now, no vaccine exists for the virus and no official treatment has been developed aside from standard procedures of the use of acetaminophen (paracetamol) and non-steroidal anti-inflammatory drugs. This is a case report of a 54 year-old Hispanic female who arrived at the clinic with symptomatology congruent with the Zika fever. The patient was treated with high doses of intravenous vitamin C over three days. The symptoms resolved after the infusions without any side effects at day four. Recovery from this viral infection takes normally around two weeks. Based on the positive outcome in this case, we propose that intravenous vitamin C should be studied further as a potential treatment for acute viral infections.

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高剂量静脉注射维生素C治疗寨卡热。
寨卡热是由黄病毒属黄病毒科单链RNA病毒引起的病毒性疾病,属于Spondweni类群。它通过蚊子媒介传播,主要是埃及伊蚊。寨卡病毒最常见的症状是发烧、皮疹、关节痛和结膜炎(红眼)。其他常见症状包括肌肉疼痛和头痛。到目前为止,除了使用对乙酰氨基酚(扑热息痛)和非甾体抗炎药的标准程序外,还没有针对该病毒的疫苗和官方治疗方法。这是一名54岁西班牙裔女性的病例报告,她抵达诊所时的症状与寨卡热相符。病人接受了三天高剂量静脉注射维生素C的治疗。注射后症状消失,第4天无任何副作用。从这种病毒感染中恢复通常需要两周左右。基于本病例的阳性结果,我们建议进一步研究静脉注射维生素C作为急性病毒感染的潜在治疗方法。
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