A Traditional NSAID Aspirin along with Clofazimine in Erythema Nodosum Leprosum Reaction: Study of Six Cases.

Q4 Medicine Indian journal of leprosy Pub Date : 2016-09-01
P K Sharma, D K Singh
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引用次数: 0

Abstract

Six male patients of lepromatous leprosy with erythema nodosum leprosum reaction (ENL) reactions diagnosed clinically and by slit skin smear were treated with aspirin and clofazimine. Aspirin was given in the daily dosage of 75mg/kg body weight up to a maximum of 2.8 grams in four divided doses, along with daily 300mg clofazimine in three divided doses and dapsone 100mg daily with rifampicin 600mg once a month. Aspirin was continued in the same dosage for a month before being tapered and stopped at the end of third month when clofazimine was also reduced to 50 mg daily. All the six cases had an excellent response in 15 days.

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传统非甾体抗炎药阿司匹林联合氯法齐明治疗麻风结节性红斑6例疗效观察
对6例经临床诊断为麻风性结节性红斑反应(ENL)的男性麻风患者,应用阿司匹林和氯法齐明治疗。阿司匹林的每日剂量为75mg/kg体重,最多可达2.8 g,分4次服用,同时氯法齐明每日300mg,分3次服用,氨苯砜每日100mg,利福平每月600mg。阿司匹林以同样的剂量持续服用一个月,然后逐渐减少,并在第三个月结束时停止服用,氯法齐明也减少到每天50毫克。6例患者均在15天内获得极好的应答。
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来源期刊
Indian journal of leprosy
Indian journal of leprosy Medicine-Dermatology
CiteScore
0.50
自引率
0.00%
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0
期刊介绍: Indian Journal of Leprosy is one of the oldest journals of India published quarterly by Hind Kusht Nivaran Sangh (Indian Leprosy Association) since 1929. The Journal covers all research aspects of leprosy, tuberculosis and other mycobacterial diseases.
期刊最新文献
Dapsone: An Update. Erythema Necroticans - A Case Report. A Traditional NSAID Aspirin along with Clofazimine in Erythema Nodosum Leprosum Reaction: Study of Six Cases. A Breast Lump in an Elderly Lady - Carcinoma or else ?. Correlates of Defaulting from MDT among Leprosy Patients.
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