Dynamics of a glucose-insulin model.

Abstract

Diabetes mellitus is a noncommunicable disease, which is a serious threat to human health around the world. In this paper, we propose a simple glucose-insulin model with Michaelis-Menten function as insulin degradation rate to mimic the pathogenic mechanism of diabetes. By theoretical analysis, a unique positive equilibrium of model exists and it is globally asymptotically stable. The four strategies are designed for diabetes patients based on the sensitivity of parameters, including insulin injection and medicine treatments. Numerical simulations are given to support the theoretical results.