Surgical Implications of Superior Thyroid Cornu Agenesis in Laryngeal Malignancy.

IF 0.7 Q4 OTORHINOLARYNGOLOGY Turkish Archives of Otorhinolaryngology Pub Date : 2022-09-01 Epub Date: 2022-11-15 DOI:10.4274/tao.2022.2022-6-16
Keshav Kumar Gupta, Zahir Mughal, Ijaz Ahmad
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Abstract

The most commonly reported superior thyroid cornu (STC) anatomical variation is in STC syndrome, where the cornu is enlarged or medially displaced. STC agenesis is a rare laryngeal variation that can be unilateral or bilateral. Previous studies have reported STC agenesis in cadaveric or forensic studies in patients with an otherwise normal larynx. We report a case of unilateral STC agenesis in the context of a stage III glottic laryngeal squamous cell carcinoma. The variation was discovered intra-operatively during a total laryngectomy and was clinically unknown beforehand. There were no clinical or histological signs of bony erosion by the tumor. To our knowledge, this is the first report of unilateral STC agenesis in a patient with laryngeal malignancy. This article draws attention to a rare anatomical variant of the larynx and highlights the surgical implications including potential diagnostic challenges and operative considerations.

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喉恶性肿瘤甲状腺上角发育不全的外科意义。
最常报道的甲状腺上角(STC)解剖变异是在STC综合征中,其中角扩大或向内侧移位。STC发育不全是一种罕见的喉部变异,可以是单侧或双侧。先前的研究报道了喉部其他部分正常的患者的尸体或法医研究中STC的发生。我们报告一例单侧STC发生在背景下的III期声门喉部鳞状细胞癌。变异是术中发现的全喉切除术和临床未知事先。没有临床或组织学上的肿瘤骨质侵蚀的迹象。据我们所知,这是喉恶性肿瘤患者单侧STC发生的第一份报告。这篇文章引起了人们对罕见的喉解剖变异的关注,并强调了手术的意义,包括潜在的诊断挑战和手术考虑。
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