Pub Date : 2024-07-03DOI: 10.4274/tao.2024.2023-12-2
Ali Can Sungur, Ö. Bayır, Gökhan Toptaş, Şevket Aksoy, Sevilay Karahan, Volkan Yücel, Emel Çadallı Tatar, G. Saylam, M. Korkmaz
locoregional-free survival (LRFS), and factors affecting recurrence were analyzed. Results: We included 573 patients with a mean age of 60.1±9.8 years. Of the 573 patients, 94.2% (540) were men, 93.7% (537) were smokers, 40.1% had at least one comorbid disease, and 69.8% (400) presented with glottic LSCC. The five-year OS, DSS, DFS, and LRFS rates for all cases were 65.7%, 79.9%, 67%, and 74.7%, respectively. In early-stage LSCC treatment, the rates of OS (p=0.008), DFS (p=0.024) and LRFS (p=0.01) were statistically significantly higher in the endolaryngeal laser surgery (ELS) group compared with the radiotherapy (RT) group. In advanced-stage LSCC treatment, total laryngectomy had statistically significantly higher five-year DFS (p=0.003) and LRFS (p=0.002) rates compared to chemoradiotherapy. Conclusion: Our study showed that ELS provided higher rates of OS, DFS, and LRFS compared to RT in the treatment of early-stage LSCC. Recurrence was significantly higher in supraglottic tumors, advanced-stage tumors, and in patients with clinical N positivity.
分析了无局部生存期（LRFS）和影响复发的因素。结果我们共纳入了573名患者，平均年龄为（60.1±9.8）岁。573例患者中，94.2%（540例）为男性，93.7%（537例）为吸烟者，40.1%至少患有一种合并症，69.8%（400例）为声门LSCC。所有病例的五年OS、DSS、DFS和LRFS率分别为65.7%、79.9%、67%和74.7%。在早期LSCC治疗中，喉内激光手术（ELS）组的OS率（P=0.008）、DFS率（P=0.024）和LRFS率（P=0.01）与放疗（RT）组相比有显著统计学差异。在晚期LSCC治疗中，与化疗放疗相比，全喉切除术的五年DFS（p=0.003）和LRFS（p=0.002）率明显更高。结论我们的研究表明，在治疗早期LSCC时，ELS的OS、DFS和LRFS率均高于RT。声门上肿瘤、晚期肿瘤和临床 N 阳性患者的复发率明显更高。
{"title":"Retrospective Analysis of Laryngeal Cancer Patients in a Tertiary Referral Center","authors":"Ali Can Sungur, Ö. Bayır, Gökhan Toptaş, Şevket Aksoy, Sevilay Karahan, Volkan Yücel, Emel Çadallı Tatar, G. Saylam, M. Korkmaz","doi":"10.4274/tao.2024.2023-12-2","DOIUrl":"https://doi.org/10.4274/tao.2024.2023-12-2","url":null,"abstract":"locoregional-free survival (LRFS), and factors affecting recurrence were analyzed. Results: We included 573 patients with a mean age of 60.1±9.8 years. Of the 573 patients, 94.2% (540) were men, 93.7% (537) were smokers, 40.1% had at least one comorbid disease, and 69.8% (400) presented with glottic LSCC. The five-year OS, DSS, DFS, and LRFS rates for all cases were 65.7%, 79.9%, 67%, and 74.7%, respectively. In early-stage LSCC treatment, the rates of OS (p=0.008), DFS (p=0.024) and LRFS (p=0.01) were statistically significantly higher in the endolaryngeal laser surgery (ELS) group compared with the radiotherapy (RT) group. In advanced-stage LSCC treatment, total laryngectomy had statistically significantly higher five-year DFS (p=0.003) and LRFS (p=0.002) rates compared to chemoradiotherapy. Conclusion: Our study showed that ELS provided higher rates of OS, DFS, and LRFS compared to RT in the treatment of early-stage LSCC. Recurrence was significantly higher in supraglottic tumors, advanced-stage tumors, and in patients with clinical N positivity.","PeriodicalId":44240,"journal":{"name":"Turkish Archives of Otorhinolaryngology","volume":null,"pages":null},"PeriodicalIF":0.7,"publicationDate":"2024-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141683390","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-03DOI: 10.4274/tao.2024.2023-6-2
Zeeshan Ali Shaikh, I. Khyani, Asad Diwan, Paras Naseem, Hasan Abbas
{"title":"Angiosarcoma Arising in a Vagal Schwannoma - Report and Literature Review","authors":"Zeeshan Ali Shaikh, I. Khyani, Asad Diwan, Paras Naseem, Hasan Abbas","doi":"10.4274/tao.2024.2023-6-2","DOIUrl":"https://doi.org/10.4274/tao.2024.2023-6-2","url":null,"abstract":"","PeriodicalId":44240,"journal":{"name":"Turkish Archives of Otorhinolaryngology","volume":null,"pages":null},"PeriodicalIF":0.7,"publicationDate":"2024-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141680979","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-06-03DOI: 10.4274/tao.2024.2024-2-2
Serpil Demir, M. Pamukçu, Selim S. Erbek
{"title":"The Effect of Rheumatoid Arthritis on Middle and Inner Ear Functions","authors":"Serpil Demir, M. Pamukçu, Selim S. Erbek","doi":"10.4274/tao.2024.2024-2-2","DOIUrl":"https://doi.org/10.4274/tao.2024.2024-2-2","url":null,"abstract":"","PeriodicalId":44240,"journal":{"name":"Turkish Archives of Otorhinolaryngology","volume":null,"pages":null},"PeriodicalIF":0.6,"publicationDate":"2024-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141270314","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-06-03DOI: 10.4274/tao.2024.2023-12-15
C. Lim, Y. Liew, Sakina Ghauth, P. Narayanan
{"title":"Case Series of Endoscopic Transoral Excision of Huge Parapharyngeal Tumors: Pushing the Boundaries","authors":"C. Lim, Y. Liew, Sakina Ghauth, P. Narayanan","doi":"10.4274/tao.2024.2023-12-15","DOIUrl":"https://doi.org/10.4274/tao.2024.2023-12-15","url":null,"abstract":"","PeriodicalId":44240,"journal":{"name":"Turkish Archives of Otorhinolaryngology","volume":null,"pages":null},"PeriodicalIF":0.6,"publicationDate":"2024-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141268776","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-05-24DOI: 10.4274/tao.2024.2023-12-9
F. Ardıç, Funda Tümkaya, A. Atıgan, F. Ardıç
{"title":"The Effect of Cochlear Implant Stimulation on Postural Control","authors":"F. Ardıç, Funda Tümkaya, A. Atıgan, F. Ardıç","doi":"10.4274/tao.2024.2023-12-9","DOIUrl":"https://doi.org/10.4274/tao.2024.2023-12-9","url":null,"abstract":"","PeriodicalId":44240,"journal":{"name":"Turkish Archives of Otorhinolaryngology","volume":null,"pages":null},"PeriodicalIF":0.6,"publicationDate":"2024-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141100306","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-05-22DOI: 10.4274/tao.2024.2023-12-10
Chandrakiran Channegowda, Soujanya Balaraj, Harshavardhan N. Reddy, Sanjay B. Patil, Surya Prakash D R, Trupthi Uthappa, Sumanth K. R.
{"title":"The Outcome of Endoscopic Sinus Surgery for Orbital Apex Syndrome Secondary to Sinusitis in a Tertiary Care Center-Our Experience Over 10 Years","authors":"Chandrakiran Channegowda, Soujanya Balaraj, Harshavardhan N. Reddy, Sanjay B. Patil, Surya Prakash D R, Trupthi Uthappa, Sumanth K. R.","doi":"10.4274/tao.2024.2023-12-10","DOIUrl":"https://doi.org/10.4274/tao.2024.2023-12-10","url":null,"abstract":"","PeriodicalId":44240,"journal":{"name":"Turkish Archives of Otorhinolaryngology","volume":null,"pages":null},"PeriodicalIF":0.6,"publicationDate":"2024-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141111130","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"IgG4-Related Disease Involving the Ear: A Case Report","authors":"Ushant Acharya, Kripa Dongol, Rabindra Bhakta Pradhananga","doi":"10.4274/tao.2024.2023-10-12","DOIUrl":"https://doi.org/10.4274/tao.2024.2023-10-12","url":null,"abstract":"","PeriodicalId":44240,"journal":{"name":"Turkish Archives of Otorhinolaryngology","volume":null,"pages":null},"PeriodicalIF":0.6,"publicationDate":"2024-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141111405","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-05-22DOI: 10.4274/tao.2024.2023-11-6
Serdar Mete, M. C. Ecevit
{"title":"Reconstruction of Anterior Skull Base After Cleaver Trauma: Combined Use of Fascia Lata and Middle Turbinate Flap in a Patient with Concha Bullosa","authors":"Serdar Mete, M. C. Ecevit","doi":"10.4274/tao.2024.2023-11-6","DOIUrl":"https://doi.org/10.4274/tao.2024.2023-11-6","url":null,"abstract":"","PeriodicalId":44240,"journal":{"name":"Turkish Archives of Otorhinolaryngology","volume":null,"pages":null},"PeriodicalIF":0.6,"publicationDate":"2024-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141111696","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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