Portal Vein Stenting for Jejunal Variceal Bleeding after Recurrence of Pancreatic Adenocarcinoma: A Case Report and Review of the Literature.

Seiichiro Takao, Masakazu Hirakawa, Kazuki Takeishi, Yushi Motomura, Katsumi Sakamoto, Hajime Otsu, Yusuke Yonemura, Koshi Mimori, Kousei Ishigami
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Abstract

A 73-year-old woman with portal vein stenosis caused by tumor recurrence after pancreatoduodenectomy was treated with stent placement without embolization of the jejunal varix. Anticoagulation therapy using heparin followed by rivaroxaban was administered after the procedure. She continued to receive systemic chemotherapy as an outpatient. Neither restenosis nor stent thrombosis was observed after 7 months. Based on the presented case and literature review, portal vein stenting is an effective treatment option for jejunal variceal bleeding caused by malignant portal venous stricture after pancreaticoduodenectomy. Antithrombotic therapy following portal venous stenting is required to prevent stent thrombosis in the majority of cases, although it has a risk of inducing recurrent variceal bleeding. Adjunctive jejunal variceal embolization can possibly be omitted in selected cases to obtain sufficient portal-SMV flow reconstruction.

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胰腺癌复发后空肠静脉曲张出血的门静脉支架置入术1例报告及文献复习。
一例73岁女性,胰十二指肠切除术后肿瘤复发导致门静脉狭窄,经支架置入治疗,空肠静脉曲张未栓塞。手术后使用肝素抗凝治疗,随后使用利伐沙班。她作为门诊病人继续接受全身化疗。7个月后未见再狭窄和支架血栓形成。根据本病例和文献回顾,门静脉支架置入术是胰十二指肠切除术后恶性门静脉狭窄引起空肠静脉曲张出血的有效治疗选择。在大多数情况下,门静脉支架植入术后需要抗血栓治疗,以防止支架血栓形成,尽管它有诱发复发性静脉曲张出血的风险。辅助空肠静脉曲张栓塞可以在某些情况下省略,以获得充分的门静脉- smv血流重建。
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