A Huge Radiation-Induced Cavernous Hemangioma Following Stereotactic Radiosurgery for Meningioma: A Case Report.

Sang Hwa Lee, Kyung Hwan Kim, Han-Joo Lee, Hyon-Jo Kwon, Seung-Won Choi, Seon-Hwan Kim, Hyeon-Song Koh, Jin-Young Youm
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Abstract

Radiation-induced cavernous hemangiomas (RICHs) have been increasingly reported as a late complication after conventional radiotherapy. RICH after stereotactic radiosurgery (SRS) is extremely rare and the few cases have been reported to demonstrate their properties. A 72-year-old female patient presented with progressive neurologic deficits. She underwent tumor surgery for meningioma 13 years ago and two times of SRS for treating a residual tumor. Newly-developed mass was 4.3 cm-sized heterogeneously enhancing mass with severe cerebral edema. She underwent surgical resection and the histologic examinations revealed organized hematoma. Finally, it was diagnosed as a RICH following SRS based on radiological and histological findings and a history of multiple radiosurgeries. Clinical, radiological, and histological features of a RICH following SRS were discussed in this report.

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立体定向放射治疗脑膜瘤后发生巨大海绵状血管瘤1例。
放射诱导海绵状血管瘤(RICHs)作为常规放射治疗后的晚期并发症已被越来越多的报道。立体定向放射手术(SRS)后的RICH是非常罕见的,很少有病例报道显示其性质。一名72岁女性患者表现为进行性神经功能缺损。13年前,她因脑膜瘤接受了肿瘤手术,并因治疗残留肿瘤接受了两次SRS。新发肿块为4.3 cm大小的非均匀强化肿块,伴严重脑水肿。手术切除,病理检查显示有组织血肿。最后,根据放射学和组织学发现以及多次放射手术史,在SRS后诊断为RICH。本报告讨论了SRS后RICH的临床、放射学和组织学特征。
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