Odontogenic Keratocyst: A Clinical Entity With Favorable Response to Active Decompression and Distraction Sugosteogenesis.

IF 0.8 Q4 DENTISTRY, ORAL SURGERY & MEDICINE Craniomaxillofacial Trauma & Reconstruction Pub Date : 2022-12-01 Epub Date: 2021-08-05 DOI:10.1177/19433875211035237
Juan-Pablo Porte, Lidia M Guerrero, Bonifacio Rivera, Andres Wiscovitch, Jaime Castro-Núñez
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引用次数: 1

Abstract

Objective: The purpose of this study was to determine the usefulness of active decompression and distraction sugosteogenesis (ADDS) for the management of non-syndromic odontogenic keratocysts (OKC).

Materials and methods: A retrospective case series study was designed and implemented. The study observed the Declaration of Helsinki on medical protocol and ethics and it was approved by the university's Institutional Review Board (IRB). The medical files of all patients who underwent ADDS for OKCs of the jaws at the Department of Oral and Maxillofacial Surgery of a tertiary university-affiliated medical center were reviewed. Data were collected on patient's age, gender, presenting signs and symptoms, lesion location, locularity, pre-ADDS, size of the lesion, post-ADDS, pain, days with bloody discharge and/or proteinaceous fluid inside the system's external unit, days to achieve hermetic seal, size of the lesion 2 weeks after ADDS, percentage of reduction, patient's complaints/complications, and follow-up period. Pre- and post-ADDS panoramic radiographs were reviewed for reduction parameters.

Results: Six patients, 5 males and 1 female, with an average age of 45.16 years (range 16-74 years) were studied. ADDS was performed during 4 weeks in all patients. During the therapy, the extraoral unit collected blood during 2.83 days in average. In average, after the third day, the cystic cavity started to drain a proteinaceous fluid for about 9.33 days (range 6-15 days). The average pre-ADDS Standard Lesional Area Index (SLAI) was 18.17 cm2 (range 4.40 cm2-34.58 m2) and, after 2 weeks of ADDS, the average SLAI was 5.47 cm2 (range 0.49 cm2-15.39 cm2). The average percentage of reduction, after 2 weeks, was 73.93% (range 55.49%-97.51%), which yielded an overall good reaction of OKCs to ADDS. No significant reduction of the lesions was observed from week 2 to week 4, when ADDS ceased. All lesions were enucleated after 3 months. After an average of 14 months of follow-up (12 to 17 months), no signs of recurrence have been observed.

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牙源性角化囊肿:一种对主动减压和牵张有良好反应的临床实体。
目的:本研究的目的是确定主动减压和牵张促骨成形术(添加)对治疗非综合征性牙源性角化囊肿(OKC)的有效性。材料和方法:设计并实施回顾性病例系列研究。该研究遵循了《赫尔辛基医疗礼仪和伦理宣言》,并得到了该大学机构审查委员会(IRB)的批准。本文回顾了某高等专科大学附属医学中心口腔颌面外科所有因颌骨OKCs而接受手术的患者的医疗档案。收集患者的年龄、性别、表现的体征和症状、病变位置、局限性、病变前、病变大小、病变后、疼痛、系统外部单元内出血和/或蛋白液体天数、达到密封的天数、病变2周后的大小、缩小的百分比、患者的投诉/并发症以及随访时间。回顾了术前和术后的全景x线片的复位参数。结果:6例患者,男5例,女1例,平均年龄45.16岁(16 ~ 74岁)。所有患者均在4周内进行了add。治疗期间,口外单位采血时间平均为2.83天。平均而言,第三天之后,囊腔开始排出蛋白液体约9.33天(范围6-15天)。add前的平均标准病变面积指数(SLAI)为18.17 cm2(范围4.40 cm2-34.58 cm2), add 2周后的平均SLAI为5.47 cm2(范围0.49 cm2-15.39 cm2)。2周后,平均减少率为73.93%(55.49% ~ 97.51%),表明OKCs对添加物的总体反应良好。从第2周到第4周,当add停止时,没有观察到明显的病变减少。3个月后所有病变均去核。经过平均14个月的随访(12 ~ 17个月),未观察到复发迹象。
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Craniomaxillofacial Trauma & Reconstruction
Craniomaxillofacial Trauma & Reconstruction DENTISTRY, ORAL SURGERY & MEDICINE-
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