Naoto Kishi, Masayuki Ogino, Isao Saito, Yoshinaga Yoshimura, Kenzo Fujimoto
{"title":"Photochemical ligation of DNA \"words\" for DNA computing.","authors":"Naoto Kishi, Masayuki Ogino, Isao Saito, Yoshinaga Yoshimura, Kenzo Fujimoto","doi":"10.1093/nass/3.1.183","DOIUrl":null,"url":null,"abstract":"<p><p>The photochemical DNA computing of 5-vinyluracil ((V)U) containing oligodeoxynucleotides (ODNs) tethered multiple \"DNA words\" is demonstrated. A new MARK and UNMARK operation based on the (V)U mediated reversible DNA photoligation has been developed for multiple-word DNA computing. The utility of this operation for DNA computing is demonstrated by solving a small Satisfiability problem (SAT problem) in which information was encoded in three tandem words.</p>","PeriodicalId":86149,"journal":{"name":"Nucleic acids research. Supplement (2001)","volume":" 3","pages":"183-4"},"PeriodicalIF":0.0000,"publicationDate":"2003-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1093/nass/3.1.183","citationCount":"2","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Nucleic acids research. Supplement (2001)","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1093/nass/3.1.183","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 2
Abstract
The photochemical DNA computing of 5-vinyluracil ((V)U) containing oligodeoxynucleotides (ODNs) tethered multiple "DNA words" is demonstrated. A new MARK and UNMARK operation based on the (V)U mediated reversible DNA photoligation has been developed for multiple-word DNA computing. The utility of this operation for DNA computing is demonstrated by solving a small Satisfiability problem (SAT problem) in which information was encoded in three tandem words.
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