The interaction between polysaccharides and other macromolecules VII. The effects of various polymers on the sedimentation rates of serum albumin and α-crystallin
{"title":"The interaction between polysaccharides and other macromolecules VII. The effects of various polymers on the sedimentation rates of serum albumin and α-crystallin","authors":"Torvard C. Laurent, Håkan Persson","doi":"10.1016/0926-6526(64)90029-1","DOIUrl":null,"url":null,"abstract":"<div><p>The sedimentation behaviour of two globular proteins of different size has been studied in solutions of polymers of varied structure. That the movement of the larger protein was in all instances retarded to a greater extent than that of the smaller indicated that the polymers investigated had a sieving effect. The ability of a polymer to inhibit the migration of another substance was demonstrated to increase with its degree of polymerization and decrease with branching. Charged substituents in a polymer were found to augment materially its effectiveness in restricting transport.</p></div>","PeriodicalId":100172,"journal":{"name":"Biochimica et Biophysica Acta (BBA) - Specialized Section on Mucoproteins and Mucopolysaccharides","volume":"83 2","pages":"Pages 141-147"},"PeriodicalIF":0.0000,"publicationDate":"1964-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0926-6526(64)90029-1","citationCount":"35","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Biochimica et Biophysica Acta (BBA) - Specialized Section on Mucoproteins and Mucopolysaccharides","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/0926652664900291","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 35
Abstract
The sedimentation behaviour of two globular proteins of different size has been studied in solutions of polymers of varied structure. That the movement of the larger protein was in all instances retarded to a greater extent than that of the smaller indicated that the polymers investigated had a sieving effect. The ability of a polymer to inhibit the migration of another substance was demonstrated to increase with its degree of polymerization and decrease with branching. Charged substituents in a polymer were found to augment materially its effectiveness in restricting transport.
京公网安备 11010802042870号
京ICP备2023020795号-1
分享
求助内容：
应助结果提醒方式：
扫码关注我们
