A comparative study between 12 and 24-dose therapeutic regimens for multibacillary leprosy patients.

Anna Maria Sales, Paulo Chagastelles Sabroza, José Augusto da Costa Nery, Nádia Cristina Duppre, Euzenir Nunes Sarno
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引用次数: 6

Abstract

A comparative study was made of the initial and final bacterial indices (BIs) of 213 MB leprosy patients who had been administered 12-dose (Group 1/128 patients) and 24-dose (Group 2/85 patients) World Health Organization multi-drug therapy to measure the effectiveness of both treatment regimens. All patients were evaluated at the beginning of treatment, at 12 months, and again after 24 months had elapsed. Decline in BI values and average BIs at 24 months were found to be similar for both groups. Moreover, no statistical difference between the two treatment regimens was found in the frequency rate of reaction.

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多菌性麻风患者12剂和24剂治疗方案的比较研究。
对213名接受世界卫生组织(who) 12剂(1/128组)和24剂(2/85组)多药治疗的MB麻风患者的初始和最终细菌指数(BIs)进行了比较研究,以衡量两种治疗方案的有效性。所有患者在治疗开始时、12个月时和24个月后再次进行评估。两组在24个月时BI值下降和平均BI值相似。此外,两种治疗方案在反应频率方面无统计学差异。
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Visible deformity in childhood leprosy--a 10-year study. Close contacts with leprosy in newly diagnosed leprosy patients in a high and low endemic area: comparison between Bangladesh and Thailand. Factors contributing to the decline of leprosy in Spain in the second half of the twentieth century. Study of apoptosis in skin lesions of leprosy in relation to treatment and lepra reactions. Myiasis in leprosy.
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