New Findings in the Multidisciplinary Management of a Fetal Intrapericardial Teratoma: A Case Report.

IF 1.6 3区 医学 Q3 OBSTETRICS & GYNECOLOGY Fetal Diagnosis and Therapy Pub Date : 2024-01-01 Epub Date: 2023-09-19 DOI:10.1159/000533132
Marco Carosso, Andrea Roberto Carosso, Gianluca Bertschy, Simona Sdei, Luca Marozio, Andrea Sciarrone, Chiara Benedetto
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Abstract

Introduction: Fetal intrapericardial teratoma is a rare tumor that can be diagnosed by antenatal ultrasonography early in pregnancy.

Case presentation: A fetal intrapericardial teratoma was detected on routine ultrasonography in the second trimester of pregnancy. At 31 weeks gestation, a marked increase in tumor size, fetal ascites, and pericardial effusion were observed, indicating that preterm delivery would be inevitable. Corticosteroid prophylaxis (24 mg of betamethasone in two doses of 12 mg 24 h apart) initiated for prophylaxis of respiratory distress syndrome led to a reduction in fetal ascites and pericardial effusion. Betamethasone therapy (4 mg/per day) was continued with the aim to postpone the expected date of delivery. Gestation was extended for more than 2 weeks. At 33 weeks and 5 days gestation, the neonate was delivered by elective cesarean section with ex utero intrapartum treatment and immediately submitted to fetal cardiac surgery. The infant was discharged from the hospital in good health about 4 months later.

Conclusion: The present report draws attention to improvement in fetal status and extension of gestation achieved with maternal low-dose corticosteroid therapy on antenatal ultrasound finding of fetal ascites and pericardial effusion due to intrapericardial teratoma.

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胎儿心包内畸胎瘤多学科治疗的新发现:一例报告。
引言胎儿心包内畸胎瘤是一种罕见的肿瘤,可在妊娠早期通过产前超声诊断。病例介绍妊娠中期常规超声检查发现胎儿心包内畸胎瘤。在妊娠31周时,观察到肿瘤大小、胎儿腹水和心包积液显著增加,这表明早产是不可避免的。为预防呼吸窘迫综合征而开始的皮质类固醇预防(24 mg倍他米松,两次12 mg,间隔24小时)可减少胎儿腹水和心包积液。继续使用倍他米松治疗(4 mg/天),目的是推迟预期分娩日期。妊娠期延长了2周以上。在妊娠33周零5天时,新生儿通过选择性剖宫产术和宫内分娩治疗(EXIT)分娩,并立即接受胎儿心脏手术。大约4个月后,婴儿出院,健康状况良好。结论本报告提请注意在产前超声检查中发现胎儿腹腔畸胎瘤引起的腹水和心包积液时,母体低剂量皮质类固醇治疗可改善胎儿状态并延长妊娠期。
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来源期刊
Fetal Diagnosis and Therapy
Fetal Diagnosis and Therapy 医学-妇产科学
CiteScore
4.70
自引率
9.10%
发文量
48
审稿时长
6-12 weeks
期刊介绍: The first journal to focus on the fetus as a patient, ''Fetal Diagnosis and Therapy'' provides a wide range of biomedical specialists with a single source of reports encompassing the common discipline of fetal medicine.
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