Roxanne Radi, Harriet Huang, Jason Rivera, Corey Lyon, Kristen DeSanto
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引用次数: 0
Abstract
YES. Low-dose naltrexone is as effective as amitriptyline in the treatment of painful diabetic neuropathy and has a superior safety profile (strength of recommendation [SOR], B; single randomized controlled trial [RCT]). Low-dose naltrexone significantly reduced pain by 32% in inflammatory conditions and 44% in neuropathic conditions (SOR, B; single retrospective cohort study). Doses as low as 5.4 mg were found to reduce pain in 95% of patients with fibromyalgia (SOR, B; single prospective dose-response study).
期刊介绍：
JFP is a peer-reviewed medical journal specifically intended to meet the needs of the specialty of family medicine. JFP is delivered to more than 95,000 family physicians as well as general practitioners and osteopaths in primary care.
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