En Qi Toh, Lester Juay, Shang-Ian Tee, Ziying Vanessa Lim
The location of the nodules and the patient's history were important diagnostic clues. The punch biopsy confirmed our suspicions.
结节的位置和患者的病史是重要的诊断线索。穿孔活检证实了我们的怀疑。
{"title":"Painless nodules on legs.","authors":"En Qi Toh, Lester Juay, Shang-Ian Tee, Ziying Vanessa Lim","doi":"10.12788/jfp.0687","DOIUrl":"10.12788/jfp.0687","url":null,"abstract":"<p><p>The location of the nodules and the patient's history were important diagnostic clues. The punch biopsy confirmed our suspicions.</p>","PeriodicalId":54836,"journal":{"name":"Journal of Family Practice","volume":"72 9","pages":"391-393"},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136400343","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aspirin demonstrated a significantly higher rate of postoperative venous thromboembolic events compared with enoxaparin in this noninferiority study.
在这项非劣效性研究中，与依诺肝素相比，阿司匹林显示出明显更高的术后静脉血栓栓塞事件发生率。
{"title":"Is low-molecular-weight heparin superior to aspirin for VTE prophylaxis?","authors":"Matthew Rose, Nilmini Pang, Sara Conway","doi":"10.12788/jfp.0698","DOIUrl":"10.12788/jfp.0698","url":null,"abstract":"<p><p>Aspirin demonstrated a significantly higher rate of postoperative venous thromboembolic events compared with enoxaparin in this noninferiority study.</p>","PeriodicalId":54836,"journal":{"name":"Journal of Family Practice","volume":"72 9","pages":"E14-E16"},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136400342","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nonalcoholic steatohepatitis, or NASH, is the most severe form of nonalcoholic fatty liver disease (NAFLD). If left untreated, NASH can develop into advanced liver disease, such as cirrhosis. Moreover, patients with NASH and cirrhosis are also at increased risk of developing hepatocellular carcinoma. Therefore, early detection and intervention are key components to prevent disease progression, particularly in the primary care setting where many patients with NASH are typically encountered.
{"title":"Clinical Consult in NASH: Are Your Patients at Risk? Based on a Medscape Education Online Activity.","authors":"Steven L Flamm","doi":"10.12788/JFP.0677","DOIUrl":"10.12788/JFP.0677","url":null,"abstract":"<p><p>Nonalcoholic steatohepatitis, or NASH, is the most severe form of nonalcoholic fatty liver disease (NAFLD). If left untreated, NASH can develop into advanced liver disease, such as cirrhosis. Moreover, patients with NASH and cirrhosis are also at increased risk of developing hepatocellular carcinoma. Therefore, early detection and intervention are key components to prevent disease progression, particularly in the primary care setting where many patients with NASH are typically encountered.</p>","PeriodicalId":54836,"journal":{"name":"Journal of Family Practice","volume":"72 9 Suppl","pages":"S3-S8"},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136400407","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Andrew V A Foley, Daniel F Farrell, Patricia Carr Reese
A fraction of those eligible for PrEP to prevent HIV infection receive a prescription. Newer drug regimens and updated recommendations can help you reduce that gap.
{"title":"Getting PrEP to the patients who need it.","authors":"Andrew V A Foley, Daniel F Farrell, Patricia Carr Reese","doi":"10.12788/jfp.0686","DOIUrl":"10.12788/jfp.0686","url":null,"abstract":"<p><p>A fraction of those eligible for PrEP to prevent HIV infection receive a prescription. Newer drug regimens and updated recommendations can help you reduce that gap.</p>","PeriodicalId":54836,"journal":{"name":"Journal of Family Practice","volume":"72 9","pages":"E1-E7"},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136400341","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
In addition to 3 vaccines, there's also a new monoclonal antibody for prevention of respiratory syncytial virus. Learn how each can be used in infants and children, adults, and pregnant people.
{"title":"Preventing RSV in children and adults: A vaccine update.","authors":"Doug Campos-Outcalt","doi":"10.12788/jfp.0699","DOIUrl":"10.12788/jfp.0699","url":null,"abstract":"<p><p>In addition to 3 vaccines, there's also a new monoclonal antibody for prevention of respiratory syncytial virus. Learn how each can be used in infants and children, adults, and pregnant people.</p>","PeriodicalId":54836,"journal":{"name":"Journal of Family Practice","volume":"72 9","pages":"E17-E20"},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136400344","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
PROBABLY NOT. In patients who have hypertension, the timing of administration of antihypertensive medications does not appear to impact cardiovascular outcomes (strength of recommendation: B; contradictory randomized controlled trials).
{"title":"Does taking BP medicine at night (vs morning) result in fewer cardiovascular events?","authors":"Robert Martin, Rick Guthmann","doi":"10.12788/jfp.0697","DOIUrl":"10.12788/jfp.0697","url":null,"abstract":"<p><p>PROBABLY NOT. In patients who have hypertension, the timing of administration of antihypertensive medications does not appear to impact cardiovascular outcomes (strength of recommendation: B; contradictory randomized controlled trials).</p>","PeriodicalId":54836,"journal":{"name":"Journal of Family Practice","volume":"72 9","pages":"E11-E13"},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136400340","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Takuya Maejima, Junki Mizumoto, Yoshiko Ito, Tomoko Suga
► history of Graves disease ► general fatigue, palpitations, and hand tremors.
►全身乏力、心悸、手颤。
{"title":"51-year-old woman • History of Graves disease • General fatigue, palpitations, and hand tremors • Dx?","authors":"Takuya Maejima, Junki Mizumoto, Yoshiko Ito, Tomoko Suga","doi":"10.12788/jfp.0690","DOIUrl":"10.12788/jfp.0690","url":null,"abstract":"<p><p>► history of Graves disease ► general fatigue, palpitations, and hand tremors.</p>","PeriodicalId":54836,"journal":{"name":"Journal of Family Practice","volume":"72 9","pages":"E8-E10"},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136400339","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Emory E Wills, Laura Beth Edwards, Robert T Brodell, Amy E Flischel
The diagnosis of this patient's inflammatory condition required us to dig deeper.
这个病人的炎症状况的诊断需要我们深入研究。
{"title":"Not acne, but what?","authors":"Emory E Wills, Laura Beth Edwards, Robert T Brodell, Amy E Flischel","doi":"10.12788/jfp.0658","DOIUrl":"10.12788/jfp.0658","url":null,"abstract":"<p><p>The diagnosis of this patient's inflammatory condition required us to dig deeper.</p>","PeriodicalId":54836,"journal":{"name":"Journal of Family Practice","volume":"72 8","pages":"353-355"},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49685222","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tristi M Edwards, Richard P Usatine, Candrice R Heath
THE JOURNAL OF FAMILY PRACTICE | OCTOBER 2023 | VOL 72, NO 8 Allergic contact dermatitis (ACD) is an inflammatory condition of the skin caused by an immunologic response to 1 or more identifiable allergens. A delayed-type immune response (type IV hypersensitivity reaction) occurs after the skin is re-exposed to an offending allergen. Severe pruritus is the main symptom of ACD in the early stages, accompanied by erythema, vesicles, and scaling in a distinct pattern corresponding to the allergen’s contact with the skin. Delayed widespread dermatitis after exposure to an allergen—a phenomenon known as autoeczematization (id reaction)—also may occur. The gold-standard diagnostic tool for ACD is patch testing, in which the patient is re-exposed to the suspected contact allergen(s) and observed for the development of dermatitis. However, ACD can be diagnosed with a detailed patient history including occupation, hobbies, personal care practices, and possible triggers with subsequent rashes. Thorough clinical examination of the skin is paramount. Indicators of possible ACD include dermatitis that persists despite use of appropriate treatment, an unexplained flare of previously quiescent dermatitis, and a diagnosis of dermatitis without a clear cause. Hairdressers, health care workers, and metal workers are at higher risk for ACD. Occupational ACD has notable socioeconomic implications, as it can result in frequent sick days, inability to perform tasks at work, and in some cases job loss. Patients with atopic dermatitis have impaired barrier function of the skin, permitting the entrance of allergens and subsequent sensitization. ACD is a challenge to manage, as complete avoidance of the allergen may not be possible. The underrepresentation of patients with skin of color (SOC) in educational materials as well as socioeconomic health disparities may contribute to the lower rates of diagnosis, patch testing, and treatment of ACD in this patient population.
{"title":"Allergic contact dermatitis.","authors":"Tristi M Edwards, Richard P Usatine, Candrice R Heath","doi":"10.12788/jfp.0678","DOIUrl":"10.12788/jfp.0678","url":null,"abstract":"THE JOURNAL OF FAMILY PRACTICE | OCTOBER 2023 | VOL 72, NO 8 Allergic contact dermatitis (ACD) is an inflammatory condition of the skin caused by an immunologic response to 1 or more identifiable allergens. A delayed-type immune response (type IV hypersensitivity reaction) occurs after the skin is re-exposed to an offending allergen. Severe pruritus is the main symptom of ACD in the early stages, accompanied by erythema, vesicles, and scaling in a distinct pattern corresponding to the allergen’s contact with the skin. Delayed widespread dermatitis after exposure to an allergen—a phenomenon known as autoeczematization (id reaction)—also may occur. The gold-standard diagnostic tool for ACD is patch testing, in which the patient is re-exposed to the suspected contact allergen(s) and observed for the development of dermatitis. However, ACD can be diagnosed with a detailed patient history including occupation, hobbies, personal care practices, and possible triggers with subsequent rashes. Thorough clinical examination of the skin is paramount. Indicators of possible ACD include dermatitis that persists despite use of appropriate treatment, an unexplained flare of previously quiescent dermatitis, and a diagnosis of dermatitis without a clear cause. Hairdressers, health care workers, and metal workers are at higher risk for ACD. Occupational ACD has notable socioeconomic implications, as it can result in frequent sick days, inability to perform tasks at work, and in some cases job loss. Patients with atopic dermatitis have impaired barrier function of the skin, permitting the entrance of allergens and subsequent sensitization. ACD is a challenge to manage, as complete avoidance of the allergen may not be possible. The underrepresentation of patients with skin of color (SOC) in educational materials as well as socioeconomic health disparities may contribute to the lower rates of diagnosis, patch testing, and treatment of ACD in this patient population.","PeriodicalId":54836,"journal":{"name":"Journal of Family Practice","volume":"72 8","pages":"350-355"},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49685216","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
This study suggests the blood pressure-lowering effects of potassium-enriched salt substitutes may reduce cardiovascular morbidity and mortality.
这项研究表明，富钾盐替代品的降压作用可以降低心血管疾病的发病率和死亡率。
{"title":"Can these salt substitutes prevent complications of hypertension?","authors":"Edward T Chang, Robert Powell, Tyler Reese","doi":"10.12788/jfp.0667","DOIUrl":"10.12788/jfp.0667","url":null,"abstract":"<p><p>This study suggests the blood pressure-lowering effects of potassium-enriched salt substitutes may reduce cardiovascular morbidity and mortality.</p>","PeriodicalId":54836,"journal":{"name":"Journal of Family Practice","volume":"72 8","pages":"342-344"},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10595026/pdf/0720342.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49685218","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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